Search Results - Life Sciences

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New Therapy to Treat Spinal Cord Injury
Treated SCI mice showed significant functional recoveryInvention Summary:Spinal cord injury (SCI) results in permanent disruption to nervous system function. There is no effective treatment to promote recovery of motor function after spinal cord injury currently available on the market. Previous research for SCI treatment was focused on targeting e...
Published: 2/12/2019   |   Inventor(s): Li Cai, Misaal Patel
Category(s): Life Sciences, Therapeutics
A Novel One-handed Cannulation Device
Invention Summary:Intravenous cannulation is routinely performed to provide reliable central venous access for administration of medical therapy. The conventional Seldinger cannulation technique is the mainstay of central line placement, however, it can lead to complications due to multiple steps and the need of changing multiple moving parts with ...
Published: 2/12/2019   |   Inventor(s): Hamid Ehsani-Nia
Category(s): Medical Devices, Life Sciences
A Method of Aggregating Environmental DNA for
Surveillance of terrestrial eDNA is achieved by: (1) Sampling of spatially distributed eDNA (2) A strategy to aggregate species-specific samples (3) Concentration of target eDNA (4) Extraction of eDNA and testingInvention Summary: Earlyrecognition and rapid eradication of exotic species can prevent detrimental ecological or economic effects. Howeve...
Published: 1/23/2019   |   Inventor(s): Rafael Valentin, Julie Lockwood, Dina Fonseca
Category(s): Life Sciences
Monoclonal Antibody for the Early Detection of Pancreatic Cancer
Immunoperoxidase staining of mAb Das-1 against low-risk IPMN (left) and high-risk IPMN (right). Gut. 2014 Oct; 63(10):1626-34; 15(11):1009-16Invention Summary:Pancreatic cancer accounts for 5% of all cancer deaths. Early stages of pancreatic cancer are often asymptomatic. As a result, patients with pancreatic cancer are often diagnosed after the ca...
Published: 12/6/2018   |   Inventor(s): Kiron Das, Koushik Das, Mari Mino-Kenudson
Category(s): Life Sciences, Diagnostics
NOCQuest: Method to Determine Number of Contributors in a DNA Mixture
Invention Summary:DNA collected at a crime scene can be used as evidence against and as a clue in the determination of the perpetrator(s) of the crime. Use of this biological evidence, however, can be complicated if DNA from multiple individuals is present. The reliability of the DNA sample can come into question as to whether a match is the resul...
Published: 12/3/2018   |   Inventor(s): Desmond Lun, Harish Swaminathan, Catherine Grgicak, Muriel Medard
Keywords(s): Alleles, DNA, Law enforcement, Software
Category(s): Life Sciences, Information Technology
Cationic Constructs Overcoming Antibiotic Resistance
Invention Summary: The spread of antibiotic resistance among bacterial pathogens in both hospital and community settings is occurring at an alarming rate, particularly to multi-drug resistant (MDR) and extensively drug resistant (XDR) bacteria. These “superbugs” resistant to multiple or to all antibiotic classes represent a serious thre...
Published: 10/29/2018   |   Inventor(s): Arkady Mustaev
Category(s): Life Sciences, Therapeutics
In Vitro Model of Liver Steatosis for Screening of Drug Compounds
The decrease in liver steatosis in hepatocytes cultured in steatosis reducing medium.Invention Summary: Donor livers are frequently rejected due to high intracellular fat content, called steatosis, which increases the risk of primary graft non-function in transplant patients. Because liver transplantation remains the only effective treatment for en...
Published: 9/19/2018   |   Inventor(s): Martin Yarmush, Nir Nativ, Francois Berthiaume, Gabriel Yarmush, Timothy Maguire, Rene Schloss
Category(s): Life Sciences, Research Tools
Novel Methods for Enhanced Efficacy of Mesenchymal Stem Cells
Plasticity of mesenchymal stem cells in immunomodulation: pathological and therapeutic implications. Nature Immunology, 2014 Nov; 15(11):1009-16Invention Summary:Clinical studies have shown that treatment with mesenchymal stem cells (MSCs) improves the condition of a number of diseases. It is generally believed that MSC-based therapy not only provi...
Published: 8/30/2018   |   Inventor(s): Yufang Shi, Guangwen Ren, Liying Zhang
Category(s): Life Sciences, Therapeutics
Biodegradable and Versatile Copolymers to Promote Wound Healing
Invention Summary:Rutgers scientists have developed a copolymer formulation to stably release salicylic acid (SA). It holds the promise for promoting topical and surgical wound healing, as SA is known to reduce local pain and inflammation as well as potentially prevent fibrous adhesion formation by reducing scar tissue. The release is stable over a...
Published: 8/29/2018   |   Inventor(s): Kathryn Uhrich, Sabrina Snyder
Keywords(s): Polymers, Wound Healing
Category(s): Life Sciences, Therapeutics
Novel System for High-Level Production of Proteins and Protein Domains
Invention Summary:The synthesis of recombinant proteins using prokaryotic expression systems has been instrumental in producing valuable reagents for biomedical research and commercial products. However, the majority of in vivo expression systems have inherent limitations in most applications--including low yields, poor quality of the expressed pro...
Published: 8/29/2018   |   Inventor(s): Gaetano Montelione, Stephen Anderson, Yuanpeng Huang, Thomas Acton
Category(s): Life Sciences, Research Tools
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