Search Results - drug delivery

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Nanotechnology-based Method for Treatment of Primary Ovarian Cancer and Prevention of Metastases
Two-in-one: Combined nanocarrier based targeted chemo and gene therapy1. Cellular penetration of naked siRNA (green) and siRNA delivered by nanocarrier (red), 2. Treatment of mice bearing metastatic ovarian cancer. a. Mice bearing xenografts of human metastatic cancer and histology of tumor tissue (before treatment), b. Mice bearing xenografts of h...
Published: 8/29/2018   |   Inventor(s): Tamara Minko, Olga Garbuzenko, Oleh Taratula, Lorna Rodriguez-Rust
Keywords(s): Drug Delivery, Oncology, therapeutic, veterinary uses
Category(s): Life Sciences, Therapeutics, Biomaterials
Formulation and Manufacture of Pharmaceuticals by Impregnation onto Porous Carriers
Figure 1. SEM Pictures of pure Neusilin® and impregnated with Fenofibrate at 30% loading.Invention Summary:Rutgers scientists have developed a novel platform of pharmaceutical product development by utilizing fluid bed impregnation (FBI) of API solutions onto porous carriers. Impregnation of solutions into porous carriers allows extremely unifo...
Published: 8/29/2018   |   Inventor(s): Fernando Muzzio, Benjamin Glasser, Plamen Grigorov
Keywords(s): Drug Delivery, Drug Delivery Methods., therapeutic
Category(s): Physical Sciences, Materials
Novel Monodisperse PEGtide Dendrons as Nanocarrier for Drug Delivery
Representative Structure of PEGtideInvention Summary: Dentrimers and dendrons have generated tremendous interest as nanocarriers for various drug delivery applications. Rutgers scientists have developed a series of novel monodisperse PEGtide dendrons with versatility to accommodate various drug delivery demands.PEGtide dendrons containing alternati...
Published: 7/24/2018   |   Inventor(s): Patrick Sinko, Jieming Gao
Keywords(s): Diagnostic Imaging, Drug Delivery, Genetic Therapy, Therapeutics
Category(s): Life Sciences, Biomaterials, Therapeutics
PolyMorphine: A Controlled Drug Delivery System for Extended Analgesia
Invention Summary:Opioid analgesics (e.g., morphine) are widely used for the treatment and management of acute and chronic pain. Morphine has a short half-life with the analgesic effect lasting only 4 to 6 hours. Hence, to maintain the drug at therapeutic levels, bolus doses at fixed intervals (every 4 hours) are administered. Currently available c...
Published: 6/13/2013   |   Inventor(s): Kathryn Uhrich, Roselin Rosario-Melendez
Keywords(s): Drug Delivery, Drug Discovery, Therapeutics
Category(s): Life Sciences, Therapeutics