|
In Vitro Model of Liver Steatosis for Screening of Drug Compounds
The decrease in liver steatosis in hepatocytes cultured in steatosis reducing medium.
Invention Summary:
Donor livers are frequently rejected due to high intracellular fat content, called steatosis, which increases the risk of primary graft non-function in transplant patients. Because liver transplantation remains the only effective treatment for...
Published: 10/12/2022
|
Inventor(s): Martin Yarmush, Nir Nativ, Francois Berthiaume, Gabriel Yarmush, Timothy Maguire, Rene Schloss
Keywords(s): Drug Discovery/Screening
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Research Tools
|
|
Ultrasound-guided Alignment and Insertion of Percutaneous Cannulating Instruments
(Left) Device prototype. (Right) Short-axis ultrasound image of segmented vessel for insertion.
Invention Summary:
Gaining access to blood vessels is a critical first step in a plethora of diagnostic and therapeutic procedures (see market applications). The timely delivery of these interventions can affect morbidity and mortality, yet in difficult...
Published: 9/8/2022
|
Inventor(s): Martin Yarmush, Alvin Chen, Max Balter, Joshua Leipheimer
Keywords(s): Cardiovascular
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Medical Devices, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Software & Algorithms
|
|
Multilayer Stackable Tissue Culture Platform for 3D Co-Culture
Invention Summary:
In a native tissue inside an animal, different types of cells co-exist and communicate with one another through the surrounding microenvironment using chemical and mechanical signaling. The lack of technology to recreate such a microenvironment in in vitro models results in either under or over prediction of results using conventional...
Published: 10/12/2022
|
Inventor(s): Martin Yarmush, Anil Shrirao, Rene Schloss, Ileana Marrero-Berrios
Keywords(s):
Category(s): Technology Classifications > Research Tools, Technology Classifications > Physical Sciences & Engineering
|
