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Multi-Faceted Anti-inflammatory Neuroprotective Nanoparticles for Treating Alzheimer’s Disease
Invention Summary:
Alzheimer's disease (AD) is characterized by progressive neurodegeneration and a high mortality rate in the elderly. Current therapeutic strategies fall short in halting the underlying cognitive decline and nerve cell damage. The primary features of AD are the accumulation of extracellular amyloid plaques, uncontrolled...
Published: 4/17/2024
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Inventor(s): Hoda Gebril, Prabhas Moghe, Kathryn Uhrich
Keywords(s):
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Nanotechnology
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Amphiphilic Polymer Stabilized Nanoparticles with Enhanced Biological Stability and Activity
Experimental oxLDL macrophage cellular uptake results after 24-hr incubation with AM micelle or NP configurations under serum free conditions (white bars), 5% FBS (gray bars) and 20% FBS (black bars).
Invention Summary:
According to Centers for Disease Control and Prevention nearly 25% of deaths in the US is due to cardiovascular...
Published: 4/17/2024
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Inventor(s): Kathryn Uhrich, Prabhas Moghe, Adam York, Robert Prud'homme
Keywords(s): Biomaterials, Cardiovascular, Drug Delivery, Nanoparticles, Polymers & Composites
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
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Multifunctional Rare Earth-Based Biophotonic Composites
Image showing use of bio-encapsulated Rare Earth (RE) doped nanoparticles targeting melanoma cells.
Invention Summary:
Researchers at Rutgers University have developed new rare earth (RE)-based light-emitting, multifunctional composites for use in various biomedical applications, such as non-invasive imaging, image–guided interventions, drug...
Published: 2/19/2024
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Inventor(s): Prabhas Moghe, Richard Riman, Charles Roth, Mei-Chee Tan, Dominik Naczynski
Keywords(s): Imaging, Nanoparticles
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Medical Imaging, Technology Classifications > Nanotechnology
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