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Biodegradable and Biocompatible Polymers for Controlled NSAID Delivery
­ ​ A. Drug delivery system hydrolysis – composed of 1 (Ibuprofen), 2 (naproxen) and 3 (tartatic acid) into polymer backbones. B. Hydrolytic degradation of the ibuprofen-based polyester. Invention Summary: Ibuprofen and naproxen are commonly used to treat pain and swelling associated with rheumatoid arthritis and osteoarthritis....
Published: 4/17/2024   |   Inventor(s): Kathryn Uhrich, Roselin Rosario-Melendez
Keywords(s): Biomaterials, Inflammation, Polymers & Composites
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
Biodegradable and Biocompatible Salicylic Acid Releasing Polymer to Enhance Diabetic Bone Regeneration
­ ​ ​​​​​​​pCT images of control and polyaspirin treated defects after 4 weeks. Graph shows average percent bone fill in defects after 4 weeks Invention Summary: Nearly 300 million people suffer from diabetes mellitus worldwide, with 25 million diabetics in the U.S. alone. Patients with diabetes are more prone to fractures, periodontitis,...
Published: 4/17/2024   |   Inventor(s): Kathryn Uhrich, Roselin Rosario-Melendez, Michelle Morano, Sabrina Snyder, Joseph Fiorellini (UPENN), Dana Graves (UPENN), Keisuke Wada (UPENN)
Keywords(s): Biomaterials, Diabetes & Metabolic Disorders, Drug Delivery, Polymers & Composites
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics