Anti-diabetic Agents from Artemisia Plants


Invention Summary:

Rutgers scientists have discovered that extracts of Artemisia plants, in particular Artemisia dracunculus, could be useful for treating Type 2 diabetes. These extracts can be rapidly and inexpensively obtained in a concentrated form (e.g., powder) by extraction using common mildly polar solvents (e.g., ethanol).

Numerous recent publications from the Rutgers team and colleagues at Pennington Biomedical Research Center (Lousiana State University) demonstrated that Russian tarragon (A. dracunculus) extracts modulate blood glucose levels and enzyme/receptor activities involved in carbohydrate metabolism. The use of A. dracunculus extracts as potential anti-diabetic agent was evaluated in multiple in vitro, in vivo and clinical studies. Experimental results suggest that the mode of action of the extracts is to increase in insulin sensitivity in muscle cells rather than is production in the pancreas.

Market Applications:

  • Type 2 Diabetes
  • Dietary Supplements
  • Functional and Medical Foods
  • Cosmetics

Advantages:

  • A. dracunculus plants can be easily grown with a minimum of time, labor, and cost
  • Extracts can be obtained using a rapid and inexpensive extraction method
  • Natural and inexpensive substance without unwanted side effects
  • Efficacy and mode of action similar to other hypoglycemic drugs
  • No known toxicity
  • Could be used in food, supplements as well as in prescription and non-prescription products

Intellectual Property & Development Status:

  • U.S. Patent 6,893,627 and related foreign patents in several countries.
  • Dr. Raskin has related technologies that are licensed to Nutrasorb. Please contact us for more information.
Rutgers ID: 2002-026
Category(s):
Agriculture
Food, Nutrition and Nutraceuticals
Contact:
Deborah Perez
Senior Licensing Manager
848-932-4467
deborah.perez@rutgers.edu
Inventors:
Ilya Raskin
David Ribnicky
Keywords:
Cosmetics
Diabetes