Novel Use of Brassinosteroids for Muscle Growth, Skin

Topical application of homobrassinolide (HB) significantly promoted wound closure. CGS-21680, positive control.


Invention Summary:

Rutgers scientists discovered a new method to promote growth, repair and maintenance of skeletal muscle and skin by using brassinosteroid compounds. 

Brassinosteroids, which are mainly found in pollen, seeds, leaves, and young vegetative tissues, are plant-specific growth hormones involved in cell division and elongation. Animal studies have shown that oral administration of brassinosteroids stimulated muscle growth, increased lean body mass and physical performance or fitness. In addition, topical application of brassinosteroids reduced inflammation, promoted skin regeneration and decreased wound healing time two-fold (image on top). Moreover, brassinosteroids increased skin elasticity and smoothness, reduced wrinkles and/or improved color. These results indicate that brassinosteroids compounds are effective for muscle and skin care and maintenance.

Market Applications:

  • Cosmetics
  • Wound Healing
  • Muscle Growth

Advantages:

  • Promote muscle growth and physical performance
  • Accelerate wound healing
  • Improve skin appearance
  • Minimal or no androgenic side effect

Intellectual Property & Development Status:

Pending patent application. Available for licensing and/or research collaboration.

Rutgers ID: 2011-096
Category(s):
Agriculture
Food, Nutrition and Nutraceuticals
Contact:
Deborah Perez
Senior Licensing Manager
848-932-4467
deborah.perez@rutgers.edu
Inventors:
Ilya Raskin
Debora Esposito
Thirum Rathinasabapathy
Keywords: