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Antioxidant-based poly(anhydride-esters)

Invention Summary: Free radicals have been identified as major sources of oxidative stress in cells leading to DNA damage. This increased oxidative stress has been implicated in various deleterious conditions including cardiovascular diseases, neurodegenerative diseases, and cancer, while also contributing to the physiology of...

Published: 4/17/2024 | Inventor(s): Kathryn Uhrich, Michelle Morano

Keywords(s): Biomaterials, Drug Delivery, Polymers & Composites

Category(s): Technology Classifications > Healthcare & Life Sciences

Biodegradable and Biocompatible Salicylic Acid Releasing Polymer to Enhance Diabetic Bone Regeneration

pCT images of control and polyaspirin treated defects after 4 weeks. Graph shows average percent bone fill in defects after 4 weeks Invention Summary: Nearly 300 million people suffer from diabetes mellitus worldwide, with 25 million diabetics in the U.S. alone. Patients with diabetes are more prone to fractures, periodontitis,...

Published: 4/17/2024 | Inventor(s): Kathryn Uhrich, Roselin Rosario-Melendez, Michelle Morano, Sabrina Snyder, Joseph Fiorellini (UPENN), Dana Graves (UPENN), Keisuke Wada (UPENN)

Keywords(s): Biomaterials, Diabetes & Metabolic Disorders, Drug Delivery, Polymers & Composites

Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics