High Affinity/Specificity Bispecific Natural Killer Cell Engager for Cancer Immunotherapy
Fig. 1: Schematic representation of the structure of a mAb (A) and a BiKE (B), and their functions. While mAbs engage NK cells with low affinity/specificity, BiKE binds to NK cells with high affinity/specificity resulting in enhanced anticancer efficacy and reduced side effects.
Monoclonal antibodies (mAb) facilitate...
Inventor(s): Arash Hatefi, Shahryar Nikkhoi
Keywords(s): Antibodies, Anti-cancer
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics, Technology Classifications > Cancer