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PSP Rating Scale: Instructional Video
Changes in scoring of PSP patients over time in three groups, categorized based on the onset age of the disease in patients.
Invention Summary:
Progressive supranuclear palsy (PSP) is a brain disorder that affects a person’s ability to move due to a gradual increase in brain cell damage over time. Symptoms of PSP increase in types and...
Published: 3/15/2024
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Inventor(s): Lawrence Golbe
Keywords(s): Neurological disorder & neuropathic pain
Category(s): Technology Classifications > Software & Copyright, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > CNS Disorder
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Techniques for Measuring Atypical Neurodevelopment in Neonates Based on Auditory Brainstem Response (ABR) Tests
Comparison of ABR signatures from neonates who showed typical (blue) or delayed and narrow, atypical (red) later diagnosed with autism spectrum disorder (ASD).
Invention Summary:
Neurodevelopmental disorders such as cerebral palsy and autism are primarily diagnosed through identification of key behaviors and symptoms. To do this, features...
Published: 12/5/2023
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Inventor(s): Elizabeth Torres
Keywords(s): Autism, Neurological disorder & neuropathic pain
Category(s): Technology Classifications > Healthcare & Life Sciences
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Dynamic Neurodevelopmental-Growth Chart of Central and Peripheral Nervous Systems
Method for data acquisition and assessments of neuromotor control development using brief video recordings.
Invention Summary:
Diagnosis of neurodevelopmental disorders relies on clinical tests that depend on observation of a set of behavioral benchmarks that are then mapped to a scale. These scales are not standardized for anatomical...
Published: 6/12/2023
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Inventor(s): Elizabeth Torres
Keywords(s): Neurological disorder & neuropathic pain
Category(s): Technology Classifications > CNS Disorder, Technology Classifications > Healthcare & Life Sciences
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Mobile Health Diagnostic for Schizophrenia
Invention Summary:
Schizophrenia is a psychiatric disorder characterized by hallucinations, disorganized thought, delusions, and a decline in both mental and physical functioning. The disorder affects about 1% of the population. Early detection and treatment significantly improves patient response to treatment; and can prevent progression to full...
Published: 11/3/2022
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Inventor(s): Thomas Papathomas, Attila Farkas
Keywords(s): Mental Health, Neurological disorder & neuropathic pain
Category(s): Technology Classifications > Software & Copyright, Technology Classifications > Medical Devices, Technology Classifications > Software & Algorithms, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics
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Modified Simmons Catheter
Neurointerventions with improved success
Invention Summary:
The global neurovascular catheter market size was valued at USD 2.88 billion in 2020 and is expected to expand at a compound annual growth rate of 6.7% from 2021 to 2028. Neurointerventionalists, interventional radiologists, cardiologists, and vascular surgeons often can have...
Published: 6/12/2023
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Inventor(s): Amit Singla
Keywords(s): Neurological disorder & neuropathic pain
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Medical Devices
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MicroRNA Based Therapeutics for Parkinson’s Disease
Protection of the mouse brain by microRNA-7 against the toxicity of a-synuclein (A) Tyrosine hydroxylase (TH) stained coronal section of mouse brain injected in the right striatum with AAV-miR-7 or non-targeting (NT) vector following by a-synuclein preformed fibrils (PFF) or PBS. (B) Substantia nigra sections. (C) Nigral dopamine neuron count. (D) Striatal...
Published: 12/9/2022
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Inventor(s): M. Maral Mouradian, Eunsung Junn
Keywords(s): Neurological disorder & neuropathic pain
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
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Biodegradable and Versatile Copolymers to Promote Wound Healing
Invention Summary:
Wound healing is a complex and dynamic process of replacing devitalized and missing cellular structures and tissue layers and thus there is a need for a biodegradable and versatile copolymers to promote wound healing.
Rutgers scientists have developed a copolymer formulation to stably release salicylic acid (SA). It holds the promise...
Published: 4/17/2024
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Inventor(s): Kathryn Uhrich, Sabrina Snyder
Keywords(s): Biomaterials, Drug Delivery, Neurological disorder & neuropathic pain, Wound healing
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
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Improved Nerve Conduits for Treatment of Peripheral Nerve Injuries
Scanning electron microscope image of conduits
Invention Summary:
Nerve conduits are used for treatment of peripheral nerve injuries. However, the current conduits are associated with poor healing resulting from swelling and reduction of luminal volume, suture pull-out, collapse, kinking, compression, and lack of mechanical strength to withstand...
Published: 12/2/2022
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Inventor(s): Joachim Kohn
Keywords(s): Biomaterials, Neurological disorder & neuropathic pain, Polymers & Composites, Wound healing
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Biomaterials
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A Chemogenetic Therapy for Neuropathic Pain
Invention Summary:
Neuropathic pain (NP) typically arises as a consequence of a lesion or disease affecting peripheral nerve fibers. Prominent features in the pathophysiology of neuropathic pain include increased, ectopic neuronal activity in pain pathways. In general, NP is frequently refractory to conventional analgesics and currently there are...
Published: 11/7/2022
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Inventor(s): Gary Aston-Jones
Keywords(s): Neurological disorder & neuropathic pain
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics, Technology Classifications > Gene Therapy
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Sigma-1 Receptor Antagonists – Non-Addictive Pain Management
Invention Summary:
The sigma 1 receptor (S1R), a molecular chaperone protein located in the endoplasmic reticulum and plasma membranes, plays important roles in various pathological disorders including pain. The potential commercial applications of novel S1R antagonists are twofold: 1) as stand-alone therapy for the treatment of chronic neuropathic...
Published: 4/21/2024
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Inventor(s): William Welsh, Youyi Peng
Keywords(s): Antiviral, Neurological disorder & neuropathic pain, Small molecules
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
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