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Novel Ricin Inhibitors
(A) Model showing the interaction of Ricin toxin A (RTA) with the P stalk to access the sarcin/ricin loop (SRL) of the eukaryotic ribosome. 26S rRNA and 60S subunit are shown in light gray and dark gray, respectively. (B) The 50% inhibitory concentration (IC50) of fragments against RTA.
Invention Summary:
Ricin toxin is lethal to human at small doses,...
Published: 12/13/2024
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Inventor(s): Nilgun Tumer, Xiao-Ping Li, Jacques Roberge, David Augeri, Bin Cao
Keywords(s): Drug Discovery/Screening
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
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