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IntelliGenes: AI/ML pipeline for biomarker discovery and patient diagnosis
A pipeline combining classical statistics and machine learning algorithms is used to identify disease-associated biomarkers and predict disease risk
Invention Summary:
Gene Expression Analysis and Genome‐wide association studies provide an unprecedented understanding of the genetic basis of human disease by uncovering millions of loci...
Published: 4/25/2024
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Inventor(s): Zeeshan Ahmed
Keywords(s):
Category(s): Technology Classifications > Artificial Intelligence & Machine Learning, Technology Classifications > Software & Algorithms, Technology Classifications > Software & Copyright, Technology Classifications > Healthcare & Life Sciences
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Novel diagnostic/prognostic biomarkers for multisystem inflammatory syndrome and SARS‐CoV‐2 infection
Schematic representation of how the proposed biomarkers can improve the diagnosis and treatment of MIS-C and COVID-19
Invention Summary:
Disease prognosis of COVID-19 has largely been influenced by multiorgan involvement. Specifically, the multiorgan involvement of multisystem inflammatory syndrome in children (MIS-C) prompts a critical...
Published: 4/4/2024
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Inventor(s):
Keywords(s):
Category(s): Technology Classifications > COVID-19, Technology Classifications > Healthcare & Life Sciences
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Novel diagnostic/prognostic biomarkers for multisystem inflammatory syndrome and SARS‐CoV‐2 infection
Schematic representation of how the proposed biomarkers can improve the diagnosis and treatment of MIS-C and COVID-19
Invention Summary:
Disease prognosis of COVID-19 has largely been influenced by multiorgan involvement. Specifically, the multiorgan involvement of multisystem inflammatory syndrome in children (MIS-C) prompts a critical need for...
Published: 4/25/2024
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Inventor(s): Jeisac Guzmán Rivera, Maria Gennaro, Dirk Moore
Keywords(s): Biomarkers
Category(s): Technology Classifications > COVID-19, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Infectious Disease
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XO-Dontia: Invisible tooth markings for increasing tooth-accuracy in dental procedures
(Left) Teeth marked with XO-Dontia under normal light exposure. (Right) The same, marked teeth when exposed to black, UV light.
Invention Summary:
Dentists use tooth numbering systems in order to mark, on referral forms and patient records, the exact teeth that must be removed via dental extractions. However, tooth numbering systems differ...
Published: 3/11/2024
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Inventor(s): Michael Conte, Nathalie Lota
Keywords(s): Polymers & Composites
Category(s): Technology Classifications > Dental, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Polymers/Composites/Materials
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A novel inhibitory mimetic peptide
slows down tumor development
Inhibitory peptide increases caspase3 activity (A) by blocking GC1/Trx1 complex thereby limiting cell proliferation by inducing cell death (B).
Invention Summary:
Soluble guanylyl cyclase (GC1) and thioredoxin 1 (Trx1), when physically interacting and attaching to each other, they acquire the ability to induce changes in other target...
Published: 4/25/2024
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Inventor(s): Annie Beuve
Keywords(s): Anti-cancer
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Cancer
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Multi-Faceted Anti-inflammatory Neuroprotective Nanoparticles for Treating Alzheimer’s Disease
Invention Summary:
Alzheimer's disease (AD) is characterized by progressive neurodegeneration and a high mortality rate in the elderly. Current therapeutic strategies fall short in halting the underlying cognitive decline and nerve cell damage. The primary features of AD are the accumulation of extracellular amyloid plaques, uncontrolled...
Published: 4/25/2024
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Inventor(s): Hoda Gebril, Prabhas Moghe, Kathryn Uhrich
Keywords(s):
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Nanotechnology
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Decentralized, Privacy-preserving Navigation Recommendation System
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The recommendation system provides a proactive and personalized route for a user’s movement indoors or outdoors.
Invention Summary:
Contact tracing has been shown to be an effective disease control measure and a key strategy for preventing further spread of the COVID-19 pandemic. However, smartphone contact tracing tools have...
Published: 2/8/2024
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Inventor(s): Dario Pompili, Saman Aliari Zonouz, Vidyasagar Sadhu
Keywords(s): Wireless
Category(s): Technology Classifications > Software & Copyright, Technology Classifications > COVID-19, Technology Classifications > Software & Algorithms, Technology Classifications > Artificial Intelligence & Machine Learning, Technology Classifications > Healthcare & Life Sciences
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Biodegradable and Biocompatible Bioactive-based Polymers - Versatile Platform Technology
Invention Summary:
The Uhrich group has developed various biodegradable polymers that chemically incorporate bioactive molecules, such as nonsteroidal anti-inflammatory drugs (e.g., salicylic acid), antioxidants (e.g., ferulic acid) and antimicrobials (e.g., carvacrol). Bioactive molecules are incorporated into polymer backbones through labile linkages,...
Published: 4/17/2024
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Inventor(s): Kathryn Uhrich, Jonathan Faig, Kervin Smith
Keywords(s): Antibacterial, Bioengineering scaffolds, Biomaterials, Drug Delivery, Polymers & Composites
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
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Novel diagnostic/prognostic biomarkers for multisystem inflammatory syndrome
Fig 1. The potential added value of testing for novel biomarkers including FCGBP, MRC1, and LBP in children with MIS-C include the quick and accurate diagnosis, treatment, and prognosis.
Invention Summary:
The multiorgan involvement of multisystem inflammatory syndrome in children (MIS-C) prompts a critical need for timely, accurate disease...
Published: 4/21/2024
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Inventor(s): Maria Gennaro, Jeisac Guzmán Rivera, Dirk Moore
Keywords(s): Biomarkers
Category(s): Technology Classifications > COVID-19, Technology Classifications > Diagnostics, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Infectious Disease
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Polyelectrolyte Complexes (PEC) for Promoting Wound Healing and Hair Growth
The pictures show the progression of wound closure and hair growth around the skin wound. Both PEC film groups show improved wound closure and signs of hair growth as early as day 21. The hair growth is primarily localized to the skin area that was under the PEC film during treatment.
Invention Summary:
Common complications of diabetes...
Published: 4/25/2024
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Inventor(s): Noshir Langrana, Francois Berthiaume, Rene Schloss, Suneel Kumar, Priya Mistry, Hwan Kang
Keywords(s):
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Physical Sciences & Engineering
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