bishr+omary - Available Technologies | Rutgers University Innovation Ventures

Search Results - bishr+omary

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PKC412 restores functionality of the keratin cytoskeleton in the skin disorder epidermolysis bullosa simplex
­​ ​ Invention Summary: Epidermolysis bullosa simplex (EBS) is a highly penetrant genetic condition that causes fragility of skin keratinocytes resulting in fluid-filled skin blisters that erode upon scratching or minor pressure on the skin. There is no good cure for EBS, and treatment typically involves preventive and/or supportive care...
Published: 6/6/2023   |   Inventor(s): Bishr Omary, Thomas Magin, Jacques Roberge, Katrin Rietscher, Pei Li
Keywords(s): Dermatology
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Rare Disease
Use of Retinoids in Congenital Erythropoietic Porphyria
Invention Summary: Congenital erythropoietic porphyria (CEP) is an unaddressed orphan disease caused by a rare genetic disorder leading to accumulation of uro/coproporphyrin-I (uro-I) in tissues due to inhibition of the enzyme uroporphyrinogen-III synthase. Clinical manifestations of CEP include bone fragility, severe photosensitivity, and photo-mutilation....
Published: 9/22/2023   |   Inventor(s): Bishr Omary, Jordan Shavit
Keywords(s): Small molecules
Category(s): Technology Classifications > Therapeutics, Technology Classifications > Healthcare & Life Sciences