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Repurposing H1 and H2 antihistamines for the treatment of erythropoietic protoporphyria
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Invention Summary:
Erythropoietic protoporphyria (EPP) is a severe genetic disorder caused by defects in heme biosynthesis, leading to the accumulation of protoporphyrin IX (PP-IX) in the liver. This accumulation results in cholestasis and, in the most severe cases, end-stage liver failure, necessitating liver transplantation or leading to...
Published: 2/4/2025
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Inventor(s): Bishr Omary, Ning Kuo
Keywords(s):
Category(s): Technology Classifications > Therapeutics, Technology Classifications > Rare Disease
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