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Therapeutic Human Monoclonal Antibody (HUMAB) with Extremely Potent and Broadly Neutralizing Activity for Omicron and Other CoV-2 Variants
Potent breadth and cross-reactivity of novel CoV2 neutralizing human monoclonal antibody that can neutralize the highly immune-evasive BQ.1/BQ.1.1 variants that are currently responsible for ≅ 50% of CoV2 infection in US.
Invention Summary:
The emergence of highly immune evasive SARS-CoV2 escape mutants require an immediate response...
Published: 1/27/2023
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Inventor(s): Alok Choudhary, Abraham Pinter
Keywords(s): Antibodies, Respiratory Disease
Category(s): Technology Classifications > Therapeutics, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > COVID-19, Technology Classifications > Diagnostics
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A Method to Predict the Response of Individual Patient to Cocktails of Radiopharmaceuticals, Chemotherapeutics or Other Agents
Representative pictures showing wide variation in cellular uptake of radiopharmaceuticals.
Invention Summary:
A number of therapeutic cocktails have been developed to treat various diseases including metastatic cancers. However, patients vary widely in their beneficial responses to such therapies. It has been found that the uptake of targeted therapeutic...
Published: 10/4/2022
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Inventor(s): Roger Howell, Behrooz Vaziri, Han Wu, Atam Dhawan
Keywords(s): Antibodies, Anti-cancer
Category(s): Technology Classifications > Software & Algorithms, Technology Classifications > Software & Copyright, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Cancer, Technology Classifications > Therapeutics
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Method to Predict the Response of Individual Patient to Cocktails of Radiopharmaceuticals, Chemotherapeutics, or Other Agents
Representative pictures showing wide variation in cellular uptake of radiopharmaceuticals.
Invention Summary:
A number of therapeutic cocktails have been developed to treat various diseases including metastatic cancers. However, patients vary widely in their beneficial responses to such therapies. It has been found that the uptake of targeted therapeutic...
Published: 8/29/2022
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Inventor(s): Roger Howell, Jordan Pasternack, John Akudugu
Keywords(s): Antibodies, Anti-cancer
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Cancer, Technology Classifications > Therapeutics
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Target Identification Focused Antibody Phage Display Technique for the Development of Cancer Therapies
Invention Summary:
Immunotherapies are proving to be one of the most effective treatments in oncology, but finding targetable tumor-associated antigens (TAA) or neoantigens remains a major impediment to develop first-in-class pharmaceuticals. Rutgers scientists developed a proteomics-based neoantigen discovery pipeline that simultaneously yields...
Published: 2/8/2022
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Inventor(s): William Belden
Keywords(s): Antibodies
Category(s): Technology Classifications > Healthcare & Life Sciences
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