respiratory+disease - Available Technologies | Rutgers University Innovation Ventures

Search Results - respiratory+disease

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A New Method to Treat Asthma and Allergic Reaction
PBS PeptideIntranasal peptide treatment inhibits ILC2-dependent mucus productionInvention Summary:Although most patients with asthma respond to regular inhaled glucocorticoid (corticosteroid) therapy, 5% to 25% of people with asthma have more severe disease and do not respond...
Published: 1/3/2020   |   Inventor(s): Mark Siracusa, Jacques Roberge
Keywords(s): Autoimmune, Peptides, Respiratory Disease
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
Novel Bronchodilator Therapy for Asthma, Chronic Obstructive Pulmonary Disease and Cystic Fibrosis by Gα12 Inhibitors and Rho Inhibitors
Figure 1 Gα12 signaling and RhoA-dependent activation of the PI3K/ROCK axis Figure 2 Gα12 siRNA attenuates carbachol-induced MLC (myosin light chain) phosphorylation in vivo. Reduced MLC phosphorylation indicates human airway smooth muscle relaxation. Carbachol activates Gα12 -coupled M3 muscarinic receptors in human airway smooth...
Published: 3/27/2018   |   Inventor(s): Reynold Panettieri, Edwin Yoo
Keywords(s): Respiratory Disease
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Research Tools, Technology Classifications > Therapeutics
Nanotechnology Approach for Inhalation Treatment of Pulmonary (Lung) Fibrosis
Inhalation Treatment Invention Summary: Idiopathic Pulmonary Fibrosis (IPF), the spontaneous development of scar tissue within the lungs, is a progressive fibrotic disease which impairs the lung’s ability to get oxygen. To date, its pathogenesis remains elusive and the survival time of patients is between three and five years. Pirfenidone,...
Published: 5/8/2013   |   Inventor(s): Tamara Minko, Vera Ivanova, Olga Garbuzenko
Keywords(s): Nanoparticles, Nanotechnology, Respiratory Disease
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics