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Immunotherapy for Inflammatory Bowel Disease (IBD)
H&E staining of colons from Zbtb20 WT and Zbtb20 cKO mice treated with DSS. Survival curves for WT and cKO mice following treatment with DSS in drinking water. Adoptive transfer of Zbtb20 expressing Tregs rescues mice from death and protects. Mice are also protected from excessive weight loss (not shown).
Invention Summary:...
Published: 10/21/2024
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Inventor(s): Derek Sant'Angelo, Lisa Denzin
Keywords(s): Autoimmune
Category(s): Technology Classifications > Healthcare & Life Sciences
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