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Search Results - martin+yarmush

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In Vitro Model of Liver Steatosis for Screening of Drug Compounds
The decrease in liver steatosis in hepatocytes cultured in steatosis reducing medium. Invention Summary: Donor livers are frequently rejected due to high intracellular fat content, called steatosis, which increases the risk of primary graft non-function in transplant patients. Because liver transplantation remains the only effective treatment for...
Published: 10/12/2022   |   Inventor(s): Martin Yarmush, Nir Nativ, Francois Berthiaume, Gabriel Yarmush, Timothy Maguire, Rene Schloss
Keywords(s): Drug Discovery/Screening
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Research Tools
Ultrasound-guided Alignment and Insertion of Percutaneous Cannulating Instruments
(Left) Device prototype. (Right) Short-axis ultrasound image of segmented vessel for insertion. Invention Summary: Gaining access to blood vessels is a critical first step in a plethora of diagnostic and therapeutic procedures (see market applications). The timely delivery of these interventions can affect morbidity and mortality, yet in difficult...
Published: 5/29/2024   |   Inventor(s): Martin Yarmush, Alvin Chen, Max Balter, Joshua Leipheimer
Keywords(s): Cardiovascular
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Medical Devices, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Software & Algorithms
Multilayer Stackable Tissue Culture Platform for 3D Co-Culture
Invention Summary: In a native tissue inside an animal, different types of cells co-exist and communicate with one another through the surrounding microenvironment using chemical and mechanical signaling. The lack of technology to recreate such a microenvironment in in vitro models results in either under or over prediction of results using conventional...
Published: 10/12/2022   |   Inventor(s): Martin Yarmush, Anil Shrirao, Rene Schloss, Ileana Marrero-Berrios
Category(s): Technology Classifications > Research Tools, Technology Classifications > Physical Sciences & Engineering