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Cationic Amphiphile for Antimicrobial Applications
The structure of CAms 5a, 5b, 5c, 8a, 8b, and 8c
Invention Summary:
The development of antibiotic-resistant bacteria is a prevalent concern that has prompted the development of new antimicrobial agents. Naturally-occurring antimicrobial peptides (AMPs) offer advantages over conventional antibiotics due to a reduced development of resistance mechanisms...
Published: 11/1/2024
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Inventor(s): Kathryn Uhrich, Yingyue Zhang, Allison Faig, Michael (mikhail) Chikindas
Keywords(s): Antibacterial, Biomaterials, Peptides
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
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Thermo-Activated Lubricant Additives for Improving Engine Efficiency and Fuel Economy
Controlled Release Friction Reduction over Time
Invention Summary:
Friction modifiers (FMs) have been extensively studied as lubricant additives that could improve lubricity of base oil friction profiles to enhance fuel economy by the petrochemical and automobile industries. There are two classes of FMs, the ash FM (organo-molybdenum molecules) and...
Published: 4/17/2024
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Inventor(s): Kathryn Uhrich, Jonathan Faig, Yingyue Zhang, Shuji LUO, Man KIT NG, Alan SCHILOWITZ, Anne SHOUGH
Keywords(s): Biomaterials, Chemical and petrochemical industry
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials
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Therapeutics for Drug-Resistant Bacterial Infections: Inhibitors of Bacterial RNA Polymerase
Invention Summary:
Bacterial infectious diseases kill 100,000 persons each year in the US and 11 million persons each year worldwide, representing nearly a fifth of deaths each year worldwide. For six decades, antibiotics have been our bulwark against bacterial infectious diseases. However, now this bulwark is collapsing. For all major bacterial...
Published: 7/7/2023
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Inventor(s): Richard Ebright, Yu Feng, Yu Zhang
Keywords(s): Antibacterial
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
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