|
Novel ChABC formulation with machine learning-guided automation
Invention Summary:
Spinal cord injury (SCI) leads to the formation of scar tissue. The scarring leads to the toughening of the extracellular matrix, or the cellular environment. One of the major concerns of SCI is the prevention of neuronal connection recovery, which can lead to paralysis or reduced control of the nervous system. For...
Published: 8/12/2025
|
Inventor(s): Adam Gormley, Matthew Tamasi, Shashank Kosuri, Michael Webb, Carlos Borca, Roshan Patel
Keywords(s): Biomaterials, Polymers & Composites, Proteins, Spinal Cord
Category(s): Technology Classifications > Biomaterials, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials, Technology Classifications > Software & Algorithms, Technology Classifications > Therapeutics
|
|
Amphiphilic macromolecules with novel hydrophobic segments
Invention Summary:
Cardiovascular diseases are the leading cause of mortality in developed countries. Atherosclerosis, defined as the buildup of lipid rich plaques within the vascular intima, is the foremost pathology underlying these conditions. This causes irregular uptake of oxidized low-density lipoproteins (OxLDL) which leads...
Published: 8/12/2025
|
Inventor(s): Kathryn Uhrich, Allison Faig, Dalia Abdelhamid, Li Gu
Keywords(s): Antibacterial, Biomaterials, Polymers & Composites
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
|
|
Amphiphilic Polymer Stabilized Nanoparticles with Enhanced Biological Stability and Activity
Experimental oxLDL macrophage cellular uptake results after 24-hr incubation with AM micelle or NP configurations under serum free conditions (white bars), 5% FBS (gray bars) and 20% FBS (black bars).
Invention Summary:
According to Centers for Disease Control and Prevention nearly 25% of deaths in the US is due to cardiovascular...
Published: 8/12/2025
|
Inventor(s): Kathryn Uhrich, Prabhas Moghe, Adam York, Robert Prud'homme
Keywords(s): Biomaterials, Cardiovascular, Drug Delivery, Nanoparticles, Polymers & Composites
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
|
|
Cellularized Nerve Regeneration Graft to Remediate Peripheral Nerve Injury
Invention Summary:
Peripheral Nerve Injuries (PNI) arising from physical trauma, cancers, or other nervous system pathologies are associated with higher costs and socioeconomic impact globally. Currently available technologies to remediate nerve injury are often unsuccessful in restoring nerve functions to its original capacity and cost of managing...
Published: 8/12/2025
|
Inventor(s): N. Sanjeeva Murthy, Zhiping Pang, Jeremy Perrelle, Jasmine Gamboa, Andrew Boreland, Amir McCormick
Keywords(s): Bioengineering scaffolds, Biomaterials, Neuropathic Pain
Category(s): Technology Classifications > Biomaterials, Technology Classifications > Healthcare & Life Sciences
|
|
Improved Nerve Conduits for Treatment of Peripheral Nerve Injuries
Scanning electron microscope image of conduits
Invention Summary:
Nerve conduits are used for treatment of peripheral nerve injuries. However, the current conduits are associated with poor healing resulting from swelling and reduction of luminal volume, suture pull-out, collapse, kinking, compression, and lack of mechanical strength to withstand...
Published: 8/12/2025
|
Inventor(s): Joachim Kohn, Basak Clements, Mindy Ezra-Sadik
Keywords(s): Biomaterials, Neurological disorder & neuropathic pain, Polymers & Composites, Wound healing
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Biomaterials
|
|
PEG Nanocarriers, Nanogels
and Synthesis Methods
Invention Summary:
A novel platform of PEG-only nanocarriers and nanogels has been developed by Rutgers scientists. The nanocarriers can be used from 100Da-100- kDa and are capable of forming stable nanogels and nanogel aggregates in a variety of sizes from 20-30nm up to >1000nm. The carriers and gels have improved solubility over existing technologies...
Published: 8/12/2025
|
Inventor(s): Patrick Sinko, Manjeet Deshmukh, Hilliard Kutscher, Stanley Stein, Simi Gunaseelan, Anupa Menjoge
Keywords(s): Biomaterials, Drug Delivery
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Biomaterials, Technology Classifications > Therapeutics
|
|
Thermo-Activated Lubricant Additives for Improving Engine Efficiency and Fuel Economy
Controlled Release Friction Reduction over Time
Invention Summary:
Friction modifiers (FMs) have been extensively studied as lubricant additives that could improve lubricity of base oil friction profiles to enhance fuel economy by the petrochemical and automobile industries. There are two classes of FMs, the ash FM (organo-molybdenum molecules) and...
Published: 8/12/2025
|
Inventor(s): Kathryn Uhrich, Jonathan Faig, Yingyue Zhang, Shuji LUO, Man KIT NG, Alan SCHILOWITZ, Anne SHOUGH
Keywords(s): Biomaterials, Chemical and petrochemical industry
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials
|
|
Biocompatible and Biodegradable Films for Effective Prevention of Postoperative Adhesions
Shear modulus of polyelectrolyte complex (PEC) films (red) compared to soft tissue and competing materials (blue).
Invention Summary:
Adhesions often form after surgery, causing chronic abdominal or pelvic pain. Currently available adhesion prevention products form only a physical barrier against adhesions and have undesirable properties, such as...
Published: 8/12/2025
|
Inventor(s): Noshir Langrana, Devendra Verma, Michelle Previtera
Keywords(s): Biomaterials
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Biomaterials, Technology Classifications > Medical Devices
|
|
Doxycycline Loaded Poly(Ethylene Glycol) Hydrogels for Healing Vesicant-Induced Ocular Wounds
Invention Summary:
Rutgers scientists have invented a method of loading poly (ethylene glycol) hydrogels with doxycycline to treat vesicant-induced (i.e. sulfur mustard gas) ocular wounds. The effectiveness of doxycycline, an FDA approved drug in humans, was previously limited in ocular treatment due to tear washing on the eye’s surface. The...
Published: 8/12/2025
|
Inventor(s): Patrick Sinko
Keywords(s): Biomaterials, Drug Delivery
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Biomaterials, Technology Classifications > Therapeutics
|
|
Fine-Tune Cellulose Crystals in Biocomposites
Morphology change from crystalline (I. Pure Cellulose) to amorphous
(III. coagulated in water) or semi-crystalline (IV. coagulated in H2O2)
Invention Summary:
Natural materials such as cellulose or silk can be used in a multitude of applications such as electrolyte batteries, filters, drug delivery systems and scaffolds for tissue engineering....
Published: 8/12/2025
|
Inventor(s): David Salas-De La Cruz, Xiao Hu, Stacy Love, David Verrill
Keywords(s): Biomaterials, Chemical and petrochemical industry, Membranes, Nanotechnology
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials
|
