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A nerve injury-specific long noncoding RNA: a new target for neuropathic pain
Relative level of nerve injury-specific RNAs in mice with sham surgery or chronic constriction injury (CCI) intrathecally administered PBS, missense oligonucleotides (MSO) or the herein designed antisense oligonucleotides (ASO) 7 days post-surgery.​ Invention Summary: 7% to 10% of the general population endure neuropathic pain, which makes up...
Published: 5/4/2023   |   Inventor(s): Yuanxiang Tao
Keywords(s): Neuropathic Pain
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Gene Therapy, Technology Classifications > Therapeutics
An Injectable and Long-Acting Local Anesthetics
Invention Summary: Local anesthetics prevent or relieve pain by interrupting nerve conduction. Even the long-acting local anesthetic agents (e.g., bupivacaine, levobupivacaine, ropivacaine) can only provide analgesia for 4-18 hours. Because of the short duration, local anesthetics often have to be given by repeated injection or continuous infusion....
Published: 10/4/2022   |   Inventor(s): Yuanxiang Tao, Xiaoyang Xu
Keywords(s): Neurological disorder & neuropathic pain, Surgery
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics