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alland%2c+david - Available Technologies | Rutgers University Innovation Ventures

Search Results - alland%2c+david

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Bact-Builder

Invention Summary: Mycobacterium tuberculosis infects a quarter of the world's population and was the second leading infectious disease killer after SARS-CoV-2 in 2020. The H37Rv strain of M. tuberculosis is widely used in laboratory experiments, but current genome assembly tools are unreliable and lack consistency. Rutgers researchers...

Published: 5/8/2023 | Inventor(s): Alland, David, Poonam Chitale, Alexander Lemenze

Keywords(s):

Category(s): Technology Classifications > Software & Algorithms, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Software & Copyright

JSF-3285, A Novel KasA Inhibitor for Tuberculosis

Figure 1. Summary profile of JSF-3285: A) In vitro profile. B) X-ray crystal structure and binding constant for complex with KasA. C) In vivo profile in mouse chronic infection model. Invention Summary: New antibacterial drugs that treat multidrug resistant mycobacterium tuberculosis (MDR TB) represent an area of high medical need. The current tuberculosis...

Published: 7/14/2023 | Inventor(s): Joel Freundlich, David Alland, Matthew Neiditch, Glenn Capodagli, Sean Ekins, Pradeep Kumar, Divya Awasthi, Daigo Inoyama

Keywords(s): Antibacterial

Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics