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Novel diagnostic/prognostic biomarkers for multisystem inflammatory syndrome and SARS‐CoV‐2 infection
Schematic representation of how the proposed biomarkers can improve the diagnosis and treatment of MIS-C and COVID-19
Invention Summary:
Disease prognosis of COVID-19 has largely been influenced by multiorgan involvement. Specifically, the multiorgan involvement of multisystem inflammatory syndrome in children (MIS-C) prompts a critical need for...
Published: 3/29/2024
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Inventor(s): Jeisac Guzmán Rivera, Maria Gennaro, Dirk Moore
Keywords(s): Biomarkers
Category(s): Technology Classifications > COVID-19, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Infectious Disease
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Novel diagnostic/prognostic biomarkers for multisystem inflammatory syndrome
Fig 1. The potential added value of testing for novel biomarkers including FCGBP, MRC1, and LBP in children with MIS-C include the quick and accurate diagnosis, treatment, and prognosis.
Invention Summary:
The multiorgan involvement of multisystem inflammatory syndrome in children (MIS-C) prompts a critical need for timely, accurate disease...
Published: 11/16/2023
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Inventor(s): Maria Gennaro, Jeisac Guzmán Rivera, Dirk Moore
Keywords(s): Biomarkers
Category(s): Technology Classifications > COVID-19, Technology Classifications > Diagnostics, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Infectious Disease
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Serological/ELISA-Based Test For COVID-19
Invention Summary:
The unprecedented outbreak and spread of SARS-CoV-2 has led to rapid development of the COVID-19 pandemic. Since its beginning in 2020, the virus has rapidly evolved due to its spread, causing the generation of novel variants like Omicron more recently. Thus, there is still an unmet need for more specific, reliable, and high throughput...
Published: 3/14/2023
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Inventor(s): Maria Gennaro, Abraham Pinter
Keywords(s):
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > COVID-19
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High-throughput gene expression screening in activated T-cells using FISH-Flow
Induction of gene expression and subsequent detection by FISH-Flow. c-fos expression is induced in activated cells, which are readily identified by FISH-Flow. GFP: negative control, GAPDH: positive control.
Invention Summary:
Many immune responses to pathological conditions involve the activation of T-cells by specific antigens. The interactions...
Published: 7/10/2023
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Inventor(s): Yuri Bushkin, Maria Gennaro, Sanjay Tyagi, Richard Pine
Keywords(s): Sensors & Probes
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics
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