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Small molecules that target RNA structures within the CoV genome
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Chemical structure of the three lead molecules derived from the focused library screen against OC43-infected Vero E6 cell screening (Zafferani et al 2021)
Invention Summary:
The SARS-CoV-2 pandemic, and the likelihood of future coronavirus pandemics, emphasized the urgent need for development of novel antivirals. Small-molecule chemical probes...
Published: 4/9/2025
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Inventor(s): Amanda Hargrove, Blanton Tolbert, Gary Brewer, Neeraj Patwardhan, Mei-Ling Li
Keywords(s): Antiviral, Respiratory Disease
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
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