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Plant-based system for generation of single-domain antibodies to combat viral infections
Plant-derived antibodies designed to target SARS- CoV-2 bind to SARS-CoV2 spike protein similar to bacteria derived antibodies based on ELISA.
Invention Summary:
The use of neutralizing antibodies is a strategy for treating viral infections, especially for individuals who are immunocompromised or have high-risk medical conditions. Mass production...
Published: 4/21/2024
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Inventor(s): Tamara Minko, Natalia Pogrebnyak, Andrew Shen, Obeid Malekshah
Keywords(s): Antiviral
Category(s): Technology Classifications > COVID-19, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics, Technology Classifications > Vaccine
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Novel Maturation‐defective Attenuated Chlamydia Vaccine
Invention Summary:
Millions of American men and women are infected with Chlamydia each year. Without proper treatment, a substantial proportion of chlamydia-infected women may develop infertility and other health problems. To date, no Chlamydia vaccine is available.
Chlamydia is an obligate intracellular bacterium with a unique...
Published: 5/2/2024
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Inventor(s): Huizhou Fan
Keywords(s): Gene editing
Category(s): Technology Classifications > Vaccine, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Infectious Disease
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Deposition of Microscale Coatings by Self-Limiting Electrospray
a. Overview of thickness-limited electrospray deposition (ESD). Electrostatically-driven spray creates a charged film which redirects charged incident droplets. b. and c. SEM images of spray results, illustrating the wide range of morphologies and particle size which can be obtained with this method(b: nanowires, c: hollow spheres).
Invention Summary:...
Published: 9/12/2024
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Inventor(s): Jonathan Singer, Lin Lei
Keywords(s): Drug Delivery
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials, Technology Classifications > COVID-19, Technology Classifications > Medical Devices, Technology Classifications > Vaccine
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A Novel Vaccine Candidate Against Fungal Infection
Vaccination with a heat-killed mutant strain combined with an adjuvant enhances protection against fungal infections in a murine model, significantly improving survival protection against WT H99 challenge. Above are a series of graphs that show vaccine efficacy using the combination vaccine in intranasal inhalation, subcutaneous injection, and intramuscular...
Published: 12/4/2024
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Inventor(s): Chaoyang Xue, Amariliz Rivera
Keywords(s): Proteins
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics, Technology Classifications > Vaccine
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