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Search Results - gaetano+montelione

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Novel System for High-Yield Production of Proteins and Protein Domains
Invention Summary: The synthesis of recombinant proteins using prokaryotic expression systems has been instrumental in producing valuable reagents for biomedical research and commercial products. However, the majority of in vivo expression systems have inherent limitations in most applications – including low yields, poor quality of the expressed...
Published: 12/1/2021   |   Inventor(s): Gaetano Montelione, Stephen Anderson, Yuanpeng Huang, Thomas Acton
Keywords(s): Drug Discovery/Screening, Manufacturing, Peptides
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Research Tools
High Efficiency Isotope Enriched Protein Production Systems
Isotopic Enrichment of Tryptic Fragments Invention Summary: Rutgers scientists have developed two Single Protein Production (SPP)-based systems to obtain high levels of specific isotopically enriched proteins: an independently inducible system (cSPP(tet)) and an amino acid auxotroph-based dual inducible system. The proprietary SPP system, developed...
Published: 8/12/2016   |   Inventor(s): Monica Roth, William Schneider, Gaetano Montelione, Masayori Inouye, Yeufeng Tang
Keywords(s): Proteins
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Research Tools