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Amphiphilic macromolecules with novel hydrophobic segments
Invention Summary:
Cardiovascular diseases are the leading cause of mortality in developed countries. Atherosclerosis, defined as the buildup of lipid rich plaques within the vascular intima, is the foremost pathology underlying these conditions. This causes irregular uptake of oxidized low-density lipoproteins (OxLDL) which leads...
Published: 4/17/2024
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Inventor(s): Kathryn Uhrich, Allison Faig, Dalia Abdelhamid, Li Gu
Keywords(s): Antibacterial, Biomaterials, Polymers & Composites
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
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Novel Ligands for Transition-Metal Catalysis
Invention Summary:
N-heterocyclic carbenes (NHCs) are tremendously valuable ligands in homogeneous catalysis. IPr (IPr = 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene) represents the most important NHC. Rutgers scientists have developed novel, sterically bulky, easily accessible NHC ligand IPr# (referred to as “hash” series) that can...
Published: 9/8/2022
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Inventor(s): Michal Szostak, Qun Zhao, Guangrong Meng, Guangchen Li
Keywords(s): Catalysts, Chemical and petrochemical industry
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Catalysts
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Diagnostic Methods for Protein Profiling
Invention Summary:
The ubiquitin/proteasome system is the major intracellular non-lysosomal proteolytic system that catalyzes the degradation of many regulatory proteins. Ubiquitin is a highly conserved 76 amino acid residue protein present in all eukaryotes. Conjugation of ubiquitin molecules to proteins marks them for degradation via the ubiquitin/proteasome...
Published: 9/8/2022
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Inventor(s): Kiran Madura, Li Chen
Keywords(s):
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Research Tools
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