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Microparticles and Machine Learning Detect Surface Receptors in a Multifrequency Microfluidic Cytometer
Graphical overview depicts the detection of electrically-sensitive cell membrane receptors: (A) Microparticles with varied aluminum oxide coatings (20nm and 10nm) are (B) coated with specific antibodies (anti-CD66b for 20 nm, anti-CD11b for 10nm) to (C) target inflammatory neutrophil receptors, resulting in cell-particle conjugates indicating...
Published: 2/6/2024
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Inventor(s): Umer Hassan, Mehdi Javanmard, Brandon Ashley
Keywords(s):
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Physical Sciences & Engineering
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Wireless Power-up and Readout of Label-free Electronic Detection of Protein Biomarkers
The schematic of the WPT system.
Invention Summary:
Electronic biosensors are involved in various applications including medical diagnostics and healthcare monitoring. Additionally, wireless power transfer is suited for remote use of biosensors without direct electrical connection. However, wireless readout of a label-free electronic biosensor...
Published: 10/5/2022
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Inventor(s): Mehdi Javanmard, Hassan Raji, Pengfei Xie, Seyed Mahmoodi
Keywords(s): Biosensor
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Medical Devices, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Sensors, Technology Classifications > Diagnostics
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Post-Print Physical Vetting of 3D Prints with Minimal Embedded Nano-Material Assessor
Overview of the Model System
Invention Summary:
3D printing has become highly desirable in industrial manufacturing and biomedical applications. Outsourcing the manufacturing to a 3D printing facility leaves the user without access to the printers and a lack of physical verification to determine whether small defects, invisible to the naked eye,...
Published: 3/17/2023
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Inventor(s): Saman Aliari Zonouz, Mehdi Javanmard, Abdul Beyah, Luis Garcia, Tuan-Anh Le, Christian Bayens
Keywords(s): Machines & Instruments, Manufacturing, Sensors & Probes
Category(s): Technology Classifications > Physical Sciences & Engineering
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Nanoelectronic Barcoding of Microparticles for Multiplexed Molecular Analysis
Invention Summary:
Capability of detecting multiple protein and nucleic acid biomarkers is crucial to disease diagnosis and precision medicine. Barcoding of microparticles is one of the most common approaches for enabling multiplexed molecular assays. Although optical and plasmonic methods for barcoding particles have been developed, instrumentations...
Published: 10/12/2022
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Inventor(s): Mehdi Javanmard
Keywords(s): Biosensor, Immunoassay
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics
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Nanowell Array Sensor Chip for Biosensing in Blood Samples
Entire multiwell plate chip and a schematic view of the 2-μm nanowell array sensor. The sensor is comprised of an array of 25 nanowells etched on the overlapping electrode surface.
Invention Summary:
The current gold-standard for protein quantification in laboratory tests is enzyme linked immunosorbent assay (ELISA), which typically relies on...
Published: 8/9/2022
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Inventor(s): Mehdi Javanmard, Pengfei Xie, Mark Allen, Wen Shen, Naixin Song
Keywords(s): Biosensor, Immunoassay
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Medical Devices, Technology Classifications > Diagnostics, Technology Classifications > COVID-19, Technology Classifications > Healthcare & Life Sciences
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Portable Exhaled Breath Condensate (EBC) Analyzer for Asthma Diagnosis and Monitoring
Invention Summary:
Asthma, an increasingly important global health problem that affects ~ 300 million people worldwide, is characterized by variable airway inflammation and air flow obstruction. Currently available non-invasive methods for diagnosing and monitoring asthma involve measurements of exhaled nitric oxide (NO). Apart from the transient...
Published: 10/12/2022
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Inventor(s): Mehdi Javanmard, Azam Gholizadeh, Robert Laumbach, Howard Kipen, Clifford Weisel, Manish Chhowalla, Andrew Gow, Damien Voiry
Keywords(s): Biosensor, Electronics
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics
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