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Paper-Based Nano-Biosensor for Cytokine Detection
se; } ​ ​ Invention Summary: Cytokines are a class of regulatory proteins that are important physiological and pathological markers commonly used for the prognosis and diagnosis of diseases such as cancer, Alzheimer’s and rheumatoid arthritis, as well as for monitoring responses to injuries. Researchers at Rutgers University have...
Published: 5/6/2022   |   Inventor(s): Aaron Mazzeo, Francois Berthiaume, Ali Ashraf, Ramendra Pal
Keywords(s): Biosensor, Graphene technology, Nanotechnology, Polymers & Composites, Sensors & Probes
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Sensors, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics, Technology Classifications > Medical Devices
Methods for Blood Pressure Estimation from Short Duration of Photoplethysmogram (PPG) Signals via Transfer Learning
­­ Invention Summary: Hypertension or high blood pressure affects a large percentage of the global adult population. Frequent self-monitoring of blood pressure (BP) is important for long-term adherence and compliance to clinical advice. However, given the intrinsic inconvenience of conventional cuff- or tonometry-based blood pressure...
Published: 2/25/2022   |   Inventor(s): Laleh Najafizadeh, Weinan Wang
Keywords(s): Biosensor, Cardiovascular
Category(s): Technology Classifications > Software & Copyright, Technology Classifications > Software & Algorithms, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics, Technology Classifications > Medical Devices, Technology Classifications > Artificial Intelligence & Machine Learning
A Method of Aggregating Environmental DNA for
Surveillance of terrestrial eDNA is achieved by: (1) Sampling of spatially distributed eDNA (2) A strategy to aggregate species-specific samples (3) Concentration of target eDNA (4) Extraction of eDNA and testing Invention Summary: Early recognition and rapid eradication of exotic species can prevent detrimental ecological or economic effects....
Published: 1/12/2022   |   Inventor(s): Rafael Valentin, Julie Lockwood, Dina Fonseca
Keywords(s): Biosensor, Pest control
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Pest Control, Technology Classifications > Physical Sciences & Engineering
High-throughput Nanoarray Screening Platform for Multi-Cellular Applications
Scope of the combinatorial nanoarray cell screening platform – varying parameters can all be contained in the CBC array to match the complexity of natural ECMs and biophysical cues. Invention Summary: Biophysical cues mediated by natural or synthetic extracellular matrices (ECMs) play an essential role in cellular reprogramming. In nature,...
Published: 11/10/2021   |   Inventor(s): Ki-Bum Lee, Letao Yang
Keywords(s): Biosensor
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Nanotechnology
Dual-Enhanced Raman Scattering-Based Nanoarray Biosensors
A schematic showing graphene-gold hybrid nanoarray for nucleic acid detection and cellular biosensing Invention Summary: Raman spectroscopy is a nondestructive, label-free technique that uses laser light to discriminate cell and tissue types. While Surface enhanced Raman scattering (SERS) has demonstrated great potential to analyze a variety of bio/chemical...
Published: 1/11/2021   |   Inventor(s): Ki-Bum Lee, Letao Yang
Keywords(s): Biosensor
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics
Graphene-Encapsulated Nanoparticle-Based Biosensor for Biomarker Detection and Its Use in Early Diagnosis of Cancer, HIV and Other Diseases
Device Schematic Invention Summary: The detection of biomarker proteins with high sensitivity and selectivity is vital for the early diagnosis of many diseases such as cancer and HIV. Rutgers scientists have developed a reduced graphene oxide encapsulated nanoparticle (rGO-NPs)-based field effect transistor (FET) biosensor for sensitive detection...
Published: 11/13/2020   |   Inventor(s): Ki-Bum Lee, Sung Myung, Aniruddh Solanki
Keywords(s): Biosensor
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Research Tools, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Nanotechnology
CerebroSense: A Brain Pulsatility Measurement Device
Invention Summary: During craniotomy, surgeons often determine the level of brain swelling based on finger tactile sensation in order to implement compensation measurements. However, under or over compensation can lead to severe complications such as cerebral ischemia. Researchers at Rutgers University and Stevens Institute of Technology have developed...
Published: 8/12/2020   |   Inventor(s): Glen Atlas, Maria Pineda, David Ferrara, Andrew Falcone, Vikki Hazelwood
Keywords(s): Biosensor
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Medical Devices
Nanoelectronic Barcoding of Microparticles for Multiplexed Molecular Analysis
Invention Summary: Capability of detecting multiple protein and nucleic acid biomarkers is crucial to disease diagnosis and precision medicine. Barcoding of microparticles is one of the most common approaches for enabling multiplexed molecular assays. Although optical and plasmonic methods for barcoding particles have been developed, instrumentations...
Published: 7/13/2020   |   Inventor(s): Mehdi Javanmard
Keywords(s): Biosensor, Immunoassay
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics
One-Step Exosome Isolation and Detection
81BD;line-height: 1;border-collapse: collapse; } Extract and concentrate exosomes immunomagnetically, analyze exosomal miRNA sensitively via metal-enhanced fluorescence effect. Invention Summary: Exosomes and their inner contents play critical roles in intercellular communication and signaling. The use of exosomes as next-generation biomarkers...
Published: 3/2/2020   |   Inventor(s): Ki-Bum Lee, Jin-Ho Lee
Keywords(s): Biosensor
Category(s): Technology Classifications > Polymers/Composites/Materials, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics
Nanowell Array Sensor Chip for Biosensing in Blood Samples
Entire multiwell plate chip and a schematic view of the 2-μm nanowell array sensor. The sensor is comprised of an array of 25 nanowells etched on the overlapping electrode surface. Invention Summary: The current gold-standard for protein quantification in laboratory tests is enzyme linked immunosorbent assay (ELISA), which typically relies on...
Published: 6/20/2018   |   Inventor(s): Mehdi Javanmard, Pengfei Xie, Mark Allen, Wen Shen, Naixin Song
Keywords(s): Biosensor, Immunoassay
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Medical Devices, Technology Classifications > Diagnostics, Technology Classifications > COVID-19, Technology Classifications > Healthcare & Life Sciences
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