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Activity-Based Aptamers as Next-Generation Bioimaging Tools and Diagnostics
Invention Summary:
As more and diverse biomarkers are identified for critical pathophysiological processes, there is a growing need to develop easily applied, reliable, and adaptable diagnostic tools.
Rutgers researchers have developed a smart molecular toolbox that fulfill these criteria. This toolbox, termed the activity-based aptamer...
Published: 9/16/2024
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Inventor(s): Enver Izgu, Tushar Aggarwal
Keywords(s): Biosensor
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics
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ESMM Biosensor for Personalized Phagocytosis Quantification in Infections
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A) Biosensor cross-sectional schematic demonstrating phagocyte with microparticles through sensing region B) Corresponding bipolar pulse generated with each passage of the cell C) Top view of biosensor where magnetic is placed on side to generate field and to modulate the cell speed
Invention Summary:
Point-of-care biomedical technologies...
Published: 5/8/2024
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Inventor(s): Umer Hassan, Corey Norton
Keywords(s): Biosensor
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Electronics/Semiconductor
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Enzyme Catalyzed Toehold Mediated Strand Displacement (TMSD)
Invention Summary:
Toehold mediated strand displacement (TMSD) is widely used in nanotechnology applications such as DNA nano-circuits and devices. The toeholds which are small single‐stranded DNA overhangs, are often utilized in kinetically controlled complex biochemical circuits. Existing toehold mediated strand displacement (TMSD)...
Published: 1/24/2023
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Inventor(s): Smita Patel, Laura Johnson, Gayatri Patel, Anupam Singh
Keywords(s): Biosensor, Catalysts, Nanotechnology
Category(s): Technology Classifications > Research Tools, Technology Classifications > Healthcare & Life Sciences
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Wireless Power-up and Readout of Label-free Electronic Detection of Protein Biomarkers
The schematic of the WPT system.
Invention Summary:
Electronic biosensors are involved in various applications including medical diagnostics and healthcare monitoring. Additionally, wireless power transfer is suited for remote use of biosensors without direct electrical connection. However, wireless readout of a label-free electronic biosensor...
Published: 5/2/2024
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Inventor(s): Mehdi Javanmard, Hassan Raji, Pengfei Xie, Seyed Mahmoodi
Keywords(s): Biosensor
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Medical Devices, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Sensors, Technology Classifications > Diagnostics
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Paper-Based Nano-Biosensor for Cytokine Detection
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Invention Summary:
Cytokines are a class of regulatory proteins that are important physiological and pathological markers commonly used for the prognosis and diagnosis of diseases such as cancer, Alzheimer’s and rheumatoid arthritis, as well as for monitoring responses to injuries.
Researchers at Rutgers University have...
Published: 6/13/2024
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Inventor(s): Aaron Mazzeo, Francois Berthiaume, Ali Ashraf, Ramendra Pal
Keywords(s): Biosensor, Graphene technology, Nanotechnology, Polymers & Composites, Sensors & Probes
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Sensors, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics, Technology Classifications > Medical Devices
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Methods for Blood Pressure Estimation from Short Duration of Photoplethysmogram (PPG) Signals via Transfer Learning
Invention Summary:
Hypertension or high blood pressure affects a large percentage of the global adult population. Frequent self-monitoring of blood pressure (BP) is important for long-term adherence and compliance to clinical advice. However, given the intrinsic inconvenience of conventional cuff- or tonometry-based blood pressure...
Published: 4/21/2024
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Inventor(s): Laleh Najafizadeh, Weinan Wang
Keywords(s): Biosensor, Cardiovascular
Category(s): Technology Classifications > Software & Copyright, Technology Classifications > Software & Algorithms, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics, Technology Classifications > Medical Devices, Technology Classifications > Artificial Intelligence & Machine Learning
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A Method of Aggregating Environmental DNA for
Surveillance of terrestrial eDNA is achieved by: (1) Sampling of spatially distributed eDNA (2) A strategy to aggregate species-specific samples (3) Concentration of target eDNA (4) Extraction of eDNA and testing
Invention Summary:
Early recognition and rapid eradication of exotic species can prevent detrimental ecological or economic effects....
Published: 6/17/2024
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Inventor(s): Rafael Valentin, Julie Lockwood, Dina Fonseca
Keywords(s): Biosensor, Pest control
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Pest Control, Technology Classifications > Physical Sciences & Engineering
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High-throughput Nanoarray Screening Platform for Multi-Cellular Applications
Scope of the combinatorial nanoarray cell screening platform – varying parameters can all be contained in the CBC array to match the complexity of natural ECMs and biophysical cues.
Invention Summary:
Biophysical cues mediated by natural or synthetic extracellular matrices (ECMs) play an essential role in cellular reprogramming. In nature,...
Published: 9/12/2024
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Inventor(s): Ki-Bum Lee, Letao Yang
Keywords(s): Biosensor
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Nanotechnology
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Dual-Enhanced Raman Scattering-Based Nanoarray Biosensors
A schematic showing graphene-gold hybrid nanoarray for nucleic acid detection and cellular biosensing
Invention Summary:
Raman spectroscopy is a nondestructive, label-free technique that uses laser light to discriminate cell and tissue types. While Surface enhanced Raman scattering (SERS) has demonstrated great potential to analyze a variety of bio/chemical...
Published: 9/12/2024
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Inventor(s): Ki-Bum Lee, Letao Yang
Keywords(s): Biosensor
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics
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CerebroSense: A Brain Pulsatility Measurement Device
Invention Summary:
During craniotomy, surgeons often determine the level of brain swelling based on finger tactile sensation in order to implement compensation measurements. However, under or over compensation can lead to severe complications such as cerebral ischemia.
Researchers at Rutgers University and Stevens Institute of Technology have developed...
Published: 6/13/2024
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Inventor(s): Glen Atlas, Maria Pineda, David Ferrara, Andrew Falcone, Vikki Hazelwood
Keywords(s): Biosensor
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Medical Devices
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