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Novel diagnostic/prognostic biomarkers for multisystem inflammatory syndrome
Fig 1. The potential added value of testing for novel biomarkers including FCGBP, MRC1, and LBP in children with MIS-C include the quick and accurate diagnosis, treatment, and prognosis.
Invention Summary:
The multiorgan involvement of multisystem inflammatory syndrome in children (MIS-C) prompts a critical need for timely, accurate disease...
Published: 11/16/2023
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Inventor(s): Maria Gennaro, Jeisac Guzmán Rivera, Dirk Moore
Keywords(s): Biomarkers
Category(s): Technology Classifications > COVID-19, Technology Classifications > Diagnostics, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Infectious Disease
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The HμB (High-Efficiency μ-Fluidic Barrier)
Figure 1. The Hμb being used with a conventional microscope stage.
Invention Summary:
In the pharmaceutical and cosmetics industries, it is pertinent to screen for safety and dosage efficacy of developed drugs and compounds. These experiments can be costly and use equipment that can only be operated by skilled technicians and...
Published: 9/13/2023
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Inventor(s): Maribel Vazquez, Juan Pena-Carvajal
Keywords(s):
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Medical Devices, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Research Tools
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Gel-Tethered Molecular Beacons for Detection of Microbes
Invention Summary:
Pathogen detection and characterization is a critical first step in the course of care for individuals suffering from these infectious diseases, and the speed by which this pathogen detection occurs can make all the difference between life or death for many patients. Currently, the gold standard for microbe quantification is either...
Published: 8/24/2023
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Inventor(s): Salvatore Marras, Xiaoguang Dai, Matthew Libera
Keywords(s): Sensors & Probes
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics
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Rapid Diagnostics of Tick-borne Diseases
Invention Summary:
Tick-borne diseases are a major health problem in the United States. Among them, Lyme disease due to the Borrelia spp., Anaplasmosis due to Anaplasma spp., and Babesiosis caused by Babesia spp., account for a large number of cases occurring throughout the country. Although treatment is readily available to combat these pathogens,...
Published: 6/6/2023
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Inventor(s): Nikhat Parveen, Salvatore Marras
Keywords(s): Disease Animal Models, Sensors & Probes
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics
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Methods of diagnosing B cell malignancies and detecting B cell malignancy relapse
Workflow schematic of the diagnostic platform for detecting B cell malignancies.
Invention Summary:
B cell malignancies comprise more than 50% of blood cancers and approximately 90% of all lymphomas. Existing technologies for the detection of B cell malignancies include modern imaging technologies, flow cytometry of B cell subpopulations, cytogenetic...
Published: 9/29/2023
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Inventor(s): Ping Xie, Jaeyong Jung, Roger Strair, Samantha Gokhale, Lauri Goodell, Amer Assal
Keywords(s): Cancer biomarkers
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Cancer, Technology Classifications > Healthcare & Life Sciences
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Therapeutic Human Monoclonal Antibody (HUMAB) with Extremely Potent and Broadly Neutralizing Activity for Omicron and Other CoV-2 Variants
Potent breadth and cross-reactivity of novel CoV2 neutralizing human monoclonal antibody that can neutralize the highly immune-evasive BQ.1/BQ.1.1 variants that are currently responsible for ≅ 50% of CoV2 infection in US.
Invention Summary:
The emergence of highly immune evasive SARS-CoV2 escape mutants require an immediate response...
Published: 1/27/2023
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Inventor(s): Alok Choudhary, Abraham Pinter
Keywords(s): Antibodies, Respiratory Disease
Category(s): Technology Classifications > Therapeutics, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > COVID-19, Technology Classifications > Diagnostics
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Mobile Health Diagnostic for Schizophrenia
Invention Summary:
Schizophrenia is a psychiatric disorder characterized by hallucinations, disorganized thought, delusions, and a decline in both mental and physical functioning. The disorder affects about 1% of the population. Early detection and treatment significantly improves patient response to treatment; and can prevent progression to full...
Published: 11/3/2022
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Inventor(s): Thomas Papathomas, Attila Farkas
Keywords(s): Mental Health, Neurological disorder & neuropathic pain
Category(s): Technology Classifications > Software & Copyright, Technology Classifications > Medical Devices, Technology Classifications > Software & Algorithms, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics
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Modified Simmons Catheter
Neurointerventions with improved success
Invention Summary:
The global neurovascular catheter market size was valued at USD 2.88 billion in 2020 and is expected to expand at a compound annual growth rate of 6.7% from 2021 to 2028. Neurointerventionalists, interventional radiologists, cardiologists, and vascular surgeons often can have...
Published: 6/12/2023
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Inventor(s): Amit Singla
Keywords(s): Neurological disorder & neuropathic pain
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Medical Devices
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Wireless Power-up and Readout of Label-free Electronic Detection of Protein Biomarkers
The schematic of the WPT system.
Invention Summary:
Electronic biosensors are involved in various applications including medical diagnostics and healthcare monitoring. Additionally, wireless power transfer is suited for remote use of biosensors without direct electrical connection. However, wireless readout of a label-free electronic biosensor...
Published: 10/5/2022
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Inventor(s): Mehdi Javanmard, Hassan Raji, Pengfei Xie, Seyed Mahmoodi
Keywords(s): Biosensor
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Medical Devices, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Sensors, Technology Classifications > Diagnostics
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Correcting Flawed Photograph Effects in Captured Medical Images
Background:
Ultrasound and other medical imaging devices scan biological structures or tissues of a patient to aid in the diagnosis of serious illnesses such as cancer. Clarity and poor quality of scanned images due to conditions associated with the patient at time of image capture, or the skill of the technician capturing the scanned image can lead...
Published: 12/2/2022
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Inventor(s): Richard Mammone, Christine Podilchuk
Keywords(s): Digital Health, Imaging
Category(s): Technology Classifications > Software & Copyright, Technology Classifications > Software & Algorithms, Technology Classifications > Artificial Intelligence & Machine Learning, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics, Technology Classifications > Medical Imaging
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