cancer+biomarkers - Available Technologies | Rutgers University Innovation Ventures

Search Results - cancer+biomarkers

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SAHMI: Microbiome-based screening method for cancer and other diseases
​ ​ Screening methodology and principle data identifying differences in microbiome diversity from disease state in pancreatic cancer Invention Summary: The microbiome plays an essential role in the prognosis and progression of disease and health, as seen in cancers like pancreatic cancer. Pancreatic cancer is rising in majority of cancer...
Published: 4/20/2022   |   Inventor(s): Subhajyoti De, Bassel Ghaddar
Keywords(s): Anti-cancer, Bioinformatics, Biomarkers, Cancer biomarkers
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics, Technology Classifications > Cancer
Biomarkers for Identifying Patients at High Risk of Progressing from Barrett’s Esophagus to Esophageal Adenocarcinoma
Invention Summary: Esophageal adenocarcinoma (EAC) has a poor prognosis with a 5-year overall survival of 15-20%. In the past 3 decades, the incidence of EAC increased 600-800%. Barrett’s esophagus (BE), the precancerous lesion for EAC, has approximately 0.11 to 1.6% annual rate of progression to EAC. Currently, the guidelines for BE surveillance...
Published: 11/30/2021   |   Inventor(s): Zhongren ("David") Zhou
Keywords(s): Anti-cancer, Biomarkers, Cancer biomarkers
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics, Technology Classifications > Cancer
An Algorithm for Identification of Treatment-response Biomarkers to Chemotherapies
Invention Summary: In the last decade, several computational methods have been successfully applied to understand cancer initiation and progression through integration of genomic and epigenomic data. However, despite recent advances in discovering a wide array of novel chemotherapy agents, identification of patients with poor and favorable response...
Published: 10/28/2021   |   Inventor(s): Antonina Mitrofanova, Nusrat Epsi
Keywords(s): Bioinformatics, Biomarkers, Cancer biomarkers, Data Science, Digital Health
Category(s): Technology Classifications > Software & Algorithms, Technology Classifications > Software & Copyright, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics
DNA Nanodevices for Point-of-Care Testing
DNA nanodevice can detect 0.1 nm microRNA Invention Summary: Point-of-Care (POC) testing is defined as a simple operated, easy-to-read, rapid and low-cost medical diagnosis that can be used by non-specialists at home, in the field or on an ambulance. It provides timely diagnostic results, enabling early diagnosis of diseases, protective therapy...
Published: 1/7/2020   |   Inventor(s): Jinglin Fu, Sung Won Oh, Adriana Pereira
Keywords(s): Bioengineering scaffolds, Biomarkers, Cancer biomarkers
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics, Technology Classifications > COVID-19, Technology Classifications > Research Tools, Technology Classifications > Infectious Disease
Small Molecule Extracellular Inhibitors of TAM Receptors for Cancer Therapy
Invention Summary: The TAM receptors (Tyro3, Axl, and Mertk) are a family of three homologous receptor tyrosine kinases (RTKs) that play important roles in tissue homeostasis, immune response, and the resolution of inflammation. Besides the intracellular catalytic kinase domain common to all kinases, the TAMs uniquely contain an extracellular domain...
Published: 12/13/2019   |   Inventor(s): William Welsh, Raymond Birge, Vladyslav Kholodovych, Youyi Peng, Stanley Kimani, Thomas Comollo
Keywords(s): Anti-cancer, Brain Cancer, Breast Cancer, Cancer biomarkers
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
New Biomarker to Guide Cancer Immunotherapy
RNA expression of ERV3-2 (for 2 different primers) is significantly higher in tumors from responders compared with tumors from non-responders. Invention Summary: Immunotherapy has led to dramatic responses in many cancer types, but only a minority of patients has clinical benefit. In certain cancers, including renal cell carcinoma, no clear correlation...
Published: 12/12/2019   |   Inventor(s): Shridar Ganesan, Gyan Bhanot, Anshuman Panda, W. Kimryn Rathmell, Aguirre de Cubas
Keywords(s): Anti-cancer, Biomarkers, Cancer biomarkers
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics, Technology Classifications > Therapeutics
Automated Detection and Classification of Tumors from Digitized Histological Tissue Specimens
Flowchart illustration of the working of the algorithm Invention Summary: Computer-aided diagnosis (CAD) systems can automatically sort digitized medical images which can otherwise be a time-consuming process. Researchers at Rutgers have developed a CAD method to automatically distinguish between tumor and benign regions in digitized prostate...
Published: 8/23/2019   |   Inventor(s): Anant Madabhushi, Michael Feldman, John Tomaszewski
Keywords(s): Cancer biomarkers, Imaging
Category(s): Technology Classifications > Software & Copyright, Technology Classifications > Software & Algorithms, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics, Technology Classifications > Medical Imaging, Technology Classifications > Artificial Intelligence & Machine Learning, Technology Classifications > Cancer
Panel & Software to Predict Therapeutic Resistance in Cancer Treatment
Invention Summary: According to the American Cancer Society, prostate cancer is the second most common malignancy in men and the second-highest cancer-related cause of death in American men. Androgen deprivation therapy (ADT), which reduces or prevents male hormones (androgens) from interacting with cancer cells, has been shown to be beneficial in...
Published: 8/23/2019   |   Inventor(s): Antonina Mitrofanova, Sukanya Panja
Keywords(s): Bioinformatics, Biomarkers, Cancer biomarkers, Prostate Cancer
Category(s): Technology Classifications > Software & Copyright, Technology Classifications > Software & Algorithms, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics
Detection of Human Endogenous Retrovirus Expression in Cancer and Normal Cells
Invention Summary: Approximately 8% of the human genome consists of sequences classified as Human endogenous retroviruses (HERVs), which are remnants of ancient retroviral integrations in the human genome. While HERV elements have degenerated over millions of years of evolution and most of them can no longer encode complete proteins, some HERV genes...
Published: 2/25/2014   |   Inventor(s): Vincent Tsiagbe, Yu Li
Keywords(s): Anti-cancer, Biomarkers, Cancer biomarkers
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Research Tools, Technology Classifications > Diagnostics, Technology Classifications > Cancer