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Prolonged Persistance of Lacticaseibacillus rhamnosus in the Digestive Tract
Recovered CFUs from daily fecal matter after repetitive autologous murine gastrointestinal track gavages. (A) Log10 of the CFU counts from fecal matter obtained after gavage of wild type L. rhamnosus (n=2). (B) Log10 of the CFU counts from fecal matter obtained after gavage of Evolution 1, which used colonies selected from gavage 1 (n=2). (C) Log10...
Published: 9/25/2025
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Inventor(s): Biju Parekkadan, Lorenzo Tosi
Keywords(s):
Category(s): Technology Classifications > Food, Nutrition and Nutraceuticals, Technology Classifications > Healthcare & Life Sciences
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High Throughput Library Preparation of Long Genomic DNA Targets
Overall workflow for preparing the LASSO library.
Invention Summary:
Advances in DNA sequencing have led to an exponential increase in the quantity of sequence data, whereas limited achievable maximum gene length (<200 bp) can produce highly biased libraries with constraints on sequence homology....
Published: 8/12/2025
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Inventor(s): Biju Parekkadan, Lorenzo Tosi
Keywords(s):
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Research Tools
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Personalized and Timed Release of Biomolecules
Invention Summary:
Protein/peptide-based therapeutics are powerful medications, however their use is often hampered by very short half-lives and the necessity for intravenous or subcutaneous injections.
Researchers from Rutgers University and Massachusetts General Hospital have developed a novel method to deliver protein/peptide-based therapeutics...
Published: 8/12/2025
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Inventor(s): Biju Parekkadan, Alexandra Burr, Alfred Tamayo
Keywords(s): Stem Cells
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Medical Devices, Technology Classifications > Cell Therapy, Technology Classifications > Gene Therapy
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