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fredric+wondisford - Available Technologies | Rutgers University Innovation Ventures

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Expanding Human Primary Liver Tissues into Functional Organoids

Invention Summary: Chronic liver diseases account for approximately two million deaths per year- one million due to complications of cirrhosis and one million due to viral hepatitis and hepatocellular carcinoma. Unfortunately, there are few treatment options for these conditions, and they commonly require organ transplants. The primary...

Published: 9/14/2022 | Inventor(s): Hatem Sabaawy, Fredric Wondisford

Keywords(s): Drug Discovery/Screening

Category(s): Technology Classifications > Cancer, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics

Modified Kisspeptin Receptor Agonist as Novel Treatment of Non-Fatty Liver Disorder and Non-Alcoholic Steatohepatitis

TAK-448 protected insulin resistant, obese mice against the development of hepatic steatosis: H& E showing fatty liver. Invention Summary: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disorder worldwide that can progress to steatohepatitis (NASH), the leading reason for liver transplants. In the U.S., there are...

Published: 4/21/2024 | Inventor(s): M. Moshmi Bhattacharya Babwah, Andy Babwah, Sally Radovick, Fredric Wondisford

Keywords(s): Diabetes & Metabolic Disorders, Peptides

Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics