Search Results - hyeon-yeol+cho

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NanoScript & MitoScript – Nanoparticles for Modulation of Endogenous DNA at the Transcription Level

NanoScript (left) for the regulation of DNA transcription and MitoScript (right) for the regulation of mDNA transcription. Invention Summary: As of 2022, 1 in 4000 people are affected by mitochondrial disorders. Currently there are no cures for many mitochondrial disorders and treatment plans typically only address alleviating...

Published: 11/25/2024 | Inventor(s): Ki-Bum Lee, Sy-Tsong Chueng, Hyeon-Yeol Cho, Young Sup Yoon

Keywords(s): Nanoparticles

Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Nanotechnology

Versatile CRISPR-Cas9 Gene Editing System

Successful gene editing in neurons differentiated from patient-derived neural stem cells. Left panel, gene editing using control guide RNA; Right panel, gene editing using MeCP2 guide RNA. Invention Summary: CRISPR-Cas-mediated genome editing makes effective gene therapy of human disease feasible. Although viral delivery of CRISPR-Cas...

Published: 9/12/2024 | Inventor(s): Ki-Bum Lee, Hyeon-Yeol Cho, Myung-Sik Yoo

Keywords(s): Gene editing

Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Rare Disease, Technology Classifications > Therapeutics