Search Results - myung-sik+yoo

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MicroRNA-7 Gene Therapy Promotes Functional Recovery Following Spinal Cord Injury

Following sever spinal cord compression, the AAV-miR-7 injected mice showed improved locomotor recovery, which is characterized by the Basso Mouse Scale (BMS). Invention Summary: Spinal cord injury (SCI) results in partial or complete loss of sensory or motor function. According to the National Spinal Cord Injury Statistical Center,...

Published: 10/21/2024 | Inventor(s): M. Maral Mouradian, Eunsung Junn, Myung-Sik Yoo

Keywords(s): Spinal Cord

Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics, Technology Classifications > Gene Therapy

Versatile CRISPR-Cas9 Gene Editing System

Successful gene editing in neurons differentiated from patient-derived neural stem cells. Left panel, gene editing using control guide RNA; Right panel, gene editing using MeCP2 guide RNA. Invention Summary: CRISPR-Cas-mediated genome editing makes effective gene therapy of human disease feasible. Although viral delivery of CRISPR-Cas...

Published: 9/12/2024 | Inventor(s): Ki-Bum Lee, Hyeon-Yeol Cho, Myung-Sik Yoo

Keywords(s): Gene editing

Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Rare Disease, Technology Classifications > Therapeutics