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CHIR99021 Loaded Polymeric Scaffolds for the Treatment of Muscle Injuries
CHIR99021 administration reduces adipocyte differentiation (as seen by lipid droplet formation) in adipogenic cultures of stem cells. (A) Oil Red O staining for lipids 14 days after adipogenic induction. (B) Quantification of Oil Red O staining after 14 and 21 days.)
Invention Summary:
The most common injury among athletes are muscle injuries,...
Published: 3/25/2025
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Inventor(s): Doga Oruc, Joseph Freeman
Keywords(s):
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Healthcare & Life Sciences
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Cell-Based Biosensor for Monitoring Neuronal Stem Cell Differentiation
Movement of fluorescent cargo (EGFP, green) from the cytoplasm to the nucleus (Hoechst, blue) as early as 10 minutes after stimulation with hippocalcin
Invention Summary:
Monitoring neuronal differentiation in stem cells is vital to advance regenerative stem cell therapies and our understanding of various neurodegenerative diseases. Traditional...
Published: 2/21/2025
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Inventor(s): Ki-Bum Lee, Youngeun Kwon, Euiyeon Lee
Keywords(s):
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Diagnostics, Technology Classifications > Medical Devices
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Use Of Generative AI and Impedance Cytometry for Ionic Microscopy and Cell Imaging
Invention Summary:
Traditional cell identification methods, often relying on complex microscopy or fluorescence-activated cell sorting (FACS), are time-consuming, and require expensive and bulky instruments. This highlights the need for more precise, rapid, and affordable diagnostic tools.
Rutgers researchers have developed a novel...
Published: 3/25/2025
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Inventor(s): Mehdi Javanmard, Gulam Rather, Mahtab Kokabi
Keywords(s):
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Medical Devices
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Modified Simmons Catheter
Neurointerventions with improved success
Invention Summary:
The global neurovascular catheter market size was valued at USD 2.88 billion in 2020 and is expected to expand at a compound annual growth rate of 6.7% from 2021 to 2028. Neurointerventionalists, interventional radiologists, cardiologists, and vascular surgeons often can have...
Published: 1/8/2025
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Inventor(s): Amit Singla
Keywords(s): Neurological disorder & neuropathic pain
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Medical Devices
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Three‐Dimensional, Load‐Sharing, Pre‐Vascularized
Scaffold for Bone Regeneration
Bi-weekly x-rays (A) showed progressive bone regeneration up to 10 weeks. The reconstructed CT images (B & C) show bone growing into and within the scaffold while the scaffolds maintained their mechanical strength.
Invention Summary:
Over 600,000 bone grafting procedures are performed in the US annually. While bone autografting is the gold...
Published: 12/11/2024
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Inventor(s): Joseph Freeman, Shreya Madhavarapu, Adhithi Lakshmikanthan
Keywords(s):
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Healthcare & Life Sciences
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Surgical Artificial Intelligence Ureteral Injury Prevention System for Robotic and Laparoscopic Surgery
Image legend: The software will offer surgeons a real‐time monitoring system for the position of the ureters
Invention Summary:
Overall incidence of significant ureteral injury in gynecologic and colorectal surgeries is 1.7% and 1.9%, respectively. The risk of injury is higher in cases with a complex history of prior surgery, radiation, inflammatory...
Published: 10/7/2024
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Inventor(s): Hussam Shwaib
Keywords(s):
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Medical Devices, Technology Classifications > Medical Imaging, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Software & Algorithms
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RED LIGHT THERAPY DEVICE FOR INTRAVENTRICULAR HEMORRHAGE IN NEWBORNS
Schematic prototype and general appearance of the external fontanelle intraventricular hemorrhage light (EFIL) device
Invention Summary:
Transcranial Photo Biomodulation (tPBM) uses light to treat brain-related diseases, such as intraventricular hemorrhage (IVH). In vivo studies on IVH-induced adult and neonatal mice show, increased clot resorption,...
Published: 6/12/2024
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Inventor(s): Garrett Gianneschi
Keywords(s): Machines & Instruments
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Healthcare & Life Sciences
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The HμB (High-Efficiency μ-Fluidic Barrier)
Figure 1. The Hμb being used with a conventional microscope stage.
Invention Summary:
In the pharmaceutical and cosmetics industries, it is pertinent to screen for safety and dosage efficacy of developed drugs and compounds. These experiments can be costly and use equipment that can only be operated by skilled technicians and...
Published: 6/13/2024
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Inventor(s): Maribel Vazquez, Juan Pena-Carvajal
Keywords(s):
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Medical Devices, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Research Tools
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Microparticles and Machine Learning Detect Surface Receptors in a Multifrequency Microfluidic Cytometer
Graphical overview depicts the detection of electrically-sensitive cell membrane receptors: (A) Microparticles with varied aluminum oxide coatings (20nm and 10nm) are (B) coated with specific antibodies (anti-CD66b for 20 nm, anti-CD11b for 10nm) to (C) target inflammatory neutrophil receptors, resulting in cell-particle conjugates indicating...
Published: 4/25/2024
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Inventor(s): Umer Hassan, Mehdi Javanmard, Brandon Ashley
Keywords(s):
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Physical Sciences & Engineering
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Elastomeric Polyurethane Sealer
New root canal sealer can more thoroughly fill gaps during root canal treatment compared to commercial sealants.
Invention Summary:
Root canal sealers are essential for filling gaps during treatment, but shrink upon setting, leaving undesirable gaps that promote infections.
Rutgers University researchers have developed Elastomeric Polyurethane...
Published: 4/25/2024
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Inventor(s): Mohammad Ali Saghiri
Keywords(s): Polymers & Composites
Category(s): Technology Classifications > Dental, Technology Classifications > Medical Devices, Technology Classifications > Polymers/Composites/Materials, Technology Classifications > Healthcare & Life Sciences
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