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Novel diagnostic/prognostic biomarkers for multisystem inflammatory syndrome
Fig 1. The potential added value of testing for novel biomarkers including FCGBP, MRC1, and LBP in children with MIS-C include the quick and accurate diagnosis, treatment, and prognosis.
Invention Summary:
The multiorgan involvement of multisystem inflammatory syndrome in children (MIS-C) prompts a critical need for timely, accurate disease...
Published: 11/16/2023
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Inventor(s): Maria Gennaro, Jeisac Guzmán Rivera, Dirk Moore
Keywords(s): Biomarkers
Category(s): Technology Classifications > COVID-19, Technology Classifications > Diagnostics, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Infectious Disease
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Polyelectrolyte Complexes (PEC) for Promoting Wound Healing and Hair Growth
The pictures show the progression of hair growth around the wound from day 21. Both PEC film groups show signs of hair growth as early as day 21. The hair growth is primarily localized to the skin area that was under the PEC film during treatment.
Invention Summary:
Common complications of diabetes include chronic, non-healing wounds of...
Published: 11/11/2023
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Inventor(s): Noshir Langrana, Francois Berthiaume, Rene Schloss, Suneel Kumar, Priya Mistry, Hwan Kang
Keywords(s):
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Physical Sciences & Engineering
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Nutraceuticals for Preventing Leaky Gut
Image Legend: Control intestinal organoids and organoids conditioned to have a leak, or more permeable barrier, were treated with nutraceuticals which clearly prevented increased permeability in the “leaky” organoids. Similar findings were observed in cell culture and in vivo
Invention Summary:
More than 22 million Americans...
Published: 10/27/2023
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Inventor(s): Ronaldo Ferraris, Nan Gao, Wei Li
Keywords(s):
Category(s): Technology Classifications > Food, Nutrition and Nutraceuticals, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
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Biologic inhibitors to reduce adverse effects of traditional opioids without compromising analgesia
Invention Summary:
Mu opioids, including morphine, fentanyl, and oxycodone, remain the mainstream drugs for moderate-to-severe pain management in the clinic despite their side-effects, such as tolerance, reward, addiction, and respiratory depression. However, misusing these mu opioids can magnify their side-effects and promote the development...
Published: 10/16/2023
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Inventor(s): Yingxian Pan
Keywords(s):
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
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RED LIGHT THERAPY DEVICE FOR INTRAVENTRICULAR HEMORRHAGE IN NEWBORNS
Schematic prototype and general appearance of the external fontanelle intraventricular hemorrhage light (EFIL) device
Invention Summary:
Transcranial Photo Biomodulation (tPBM) uses light to treat brain-related diseases, such as intraventricular hemorrhage (IVH). In vivo studies on IVH-induced adult and neonatal mice show, increased clot resorption,...
Published: 9/25/2023
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Inventor(s): Garrett Gianneschi
Keywords(s): Machines & Instruments
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Healthcare & Life Sciences
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Off-the-Shelf CAR-Macrophages for Solid Tumors
Invention Summary:
Chimeric Antigen Receptor (CAR) therapy requires isolation of the respective immune cells from the patient’s blood, genetic manipulation, and infusion of the modified cells back into the patient’s body. This makes it personalized and effective but expensive. The CAR-T (modified T cells) therapy has shown...
Published: 10/26/2023
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Inventor(s): Pingping Hou
Keywords(s): Anti-cancer
Category(s): Technology Classifications > Cell Therapy, Technology Classifications > Cancer, Technology Classifications > Healthcare & Life Sciences
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Dynamic Light Spectrum Absorption Eyewear
A perspective view of some components of eyewear
Invention Summary:
Chromotherapy or Colorology is a known holistic or alternative treatment which has been used for healing and psychological well-being of an individual. Qualitative and quantitative data exists that demonstrates the impact of color on an individual’s psychological...
Published: 9/20/2023
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Inventor(s): Glenn Amatucci, Alexandra Amatucci
Keywords(s):
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Energy & Battery, Technology Classifications > Healthcare & Life Sciences
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The HμB (High-Efficiency μ-Fluidic Barrier)
Figure 1. The Hμb being used with a conventional microscope stage.
Invention Summary:
In the pharmaceutical and cosmetics industries, it is pertinent to screen for safety and dosage efficacy of developed drugs and compounds. These experiments can be costly and use equipment that can only be operated by skilled technicians and...
Published: 9/13/2023
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Inventor(s): Maribel Vazquez, Juan Pena-Carvajal
Keywords(s):
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Medical Devices, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Research Tools
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Microparticles and Machine Learning Detect Surface Receptors in a Multifrequency Microfluidic Cytometer
Graphical overview depicts the detection of electrically-sensitive cell membrane receptors: (A) Microparticles with varied aluminum oxide-coatings (20nm and 10nm) are (B) coated with specific antibodies (anti-CD66b for 20 nm, anti-CD11b for 10nm) to (C) target inflammatory neutrophil receptors, resulting in cell-particle conjugates indicating...
Published: 9/1/2023
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Inventor(s): Umer Hassan, Mehdi Javanmard, Brandon Ashley
Keywords(s):
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Physical Sciences & Engineering
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Gel-Tethered Molecular Beacons for Detection of Microbes
Invention Summary:
Pathogen detection and characterization is a critical first step in the course of care for individuals suffering from these infectious diseases, and the speed by which this pathogen detection occurs can make all the difference between life or death for many patients. Currently, the gold standard for microbe quantification is either...
Published: 8/24/2023
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Inventor(s): Salvatore Marras, Xiaoguang Dai, Matthew Libera
Keywords(s): Sensors & Probes
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics
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