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Antiviral Compositions for Enterovirus D68 and an FP-Based Method for Validating Candidate Compounds
Invention Portfolio Summary:
Enterovirus D68 (EV-D68) is an RNA virus in the Picornaviridae family, is a re-emerging pediatric pathogen associated with recurrent outbreaks, can cause severe respiratory disease, and has also been linked to acute flaccid myelitis (AFM), whose incidence has risen steadily over the past decade. There are no approved...
Published: 3/27/2026
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Category(s): Technology Classifications > Healthcare & Life Sciences
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Non-Invasive Closed-Loop Diaphragmatic Pacer for SUDEP Prevention
Invention Summary:
Epileptic seizures can cause central respiratory arrest, a phenomenon called Sudden Unexpected Death in Epilepsy (SUDEP) which needs immediate respiratory support within 3 minutes to avoid death. The absence of reliable biomarkers further limits preventive measures to avoid SUDEP. Here, a wearable diaphragmatic pacer that...
Published: 3/27/2026
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Inventor(s): Benton Purnell, Detlev Boison, Simiao Niu
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Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Medical Devices
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AN INTRA-OCULAR METHOD TO TREAT NEUROPSYCHIATRIC DISORDERS
Figure A indicates in rats the latency as a measure of time to escape from a maze. Figure B indicates AD rats with PRAM therapeutic showed less time to escape the maze, demonstrating improved memory and spatial recall
Invention Summary:
Alzheimer’s disease (AD) affects over 55 million people worldwide and is projected to triple by 2050....
Published: 3/4/2026
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Category(s): Technology Classifications > Healthcare & Life Sciences
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Enhancers for gene delivery to specific motor neuron subtypes
Enhancers demonstrating motor neuron subtype specificity
Invention Summary:
Specific types of motor neurons become dysfunctional and degenerate in motor neurons diseases like amyotrophic lateral sclerosis and Charcot Marie tooth syndrome. To reduce the risk of toxicity from ubiquitous or non-specific expression of gene therapies, there is...
Published: 2/20/2026
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Inventor(s): Tulsi Patel, Yijia Chen
Keywords(s):
Category(s): Technology Classifications > Healthcare & Life Sciences
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Electrotherapy for dental implants
In Situ electrochemical repassivation therapy of titanium dental implants can restore corrosion resistance and enhance cellular biocompatibility.
Invention Summary:
Peri-implantitis affects up to 25% of dental implant patients and is a leading cause of implant failure, representing a global market burden exceeding $1B annually. Current treatments...
Published: 3/10/2026
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Inventor(s): Georgios Kotsakis, Li Xie
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Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Dental
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Method for Enhancing Immunoregulatory Effect of Stem Cells
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IL-17A promotes MSC-Mediated immunosupressive effect. Changes in cell proliferation as shown in microscopy
Invention Summary:
Autoimmune diseases occur when the immune system attacks the body’s tissue components. Mesenchymal stem/stromal cells (MSCs) have been used as treatment to many autoimmune disorders such as type 1 diabetes,...
Published: 3/6/2026
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Inventor(s): Yufang Shi, Guangwen Ren, Liying Zhang
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Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics, Technology Classifications > Cell Therapy
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Diagnostic Assays and Methods for Detecting Pathogens
A novel sample processing method for the co-extraction of DNA/RNA from Mycobacterium tuberculosis (TB) and SARS-COV-2, complementing a novel near-patient CRISPR test for tuberculosis detection (CRISPR SHINE TB).
Invention Summary:
Tuberculosis and COVID-19 are infectious diseases with high mortality rates caused by Mycobacterium tuberculosis...
Published: 2/20/2026
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Inventor(s): Padmapriya Banada, Nisha Modi, Alexandra Bell, Owen Dunkley, Yingda Xie, Cameron Myhrvold
Keywords(s):
Category(s): Technology Classifications > Diagnostics, Technology Classifications > COVID-19, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Infectious Disease
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Novel diagnostics measures clock gene expression for early detection of fetal alcohol spectrum disorder
Novel salivary diagnostic test to measure circadian clock gene expression in FASD children using saliva samples.
Invention Summary:
Alcohol drinking during pregnancy leads to fetal alcohol spectrum disorder (FASD) accounting for about 2-5% of children in North America. Early diagnosis of FASD is imperative to prevent brain...
Published: 2/20/2026
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Inventor(s): Dipak Sarkar
Keywords(s):
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics
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Prolonged Persistance of Lacticaseibacillus rhamnosus in the Digestive Tract
Recovered CFUs from daily fecal matter after repetitive autologous murine gastrointestinal track gavages. (A) Log10 of the CFU counts from fecal matter obtained after gavage of wild type L. rhamnosus (n=2). (B) Log10 of the CFU counts from fecal matter obtained after gavage of Evolution 1, which used colonies selected from gavage 1 (n=2). (C) Log10...
Published: 2/20/2026
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Inventor(s): Biju Parekkadan, Lorenzo Tosi
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Category(s): Technology Classifications > Food, Nutrition and Nutraceuticals, Technology Classifications > Healthcare & Life Sciences
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The MaxVac powered toothbrush: Suction Toothbrush and Related Methods
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Vacuum-Tooth Brush Attributes: On-off switch, Vaccum power (hi-low), Easy-Empty (or disposable) fluid & debris collector cup, Ergonomic design, Battery-operated and Affordable.
Invention Summary:
There is a need for a powered toothbrush that has a built-in...
Published: 2/20/2026
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Inventor(s): Maxine Strickland, Glennon Simmons, Dominic Peralta
Keywords(s): Personal Care, Cosmeceuticals
Category(s): Technology Classifications > Dental, Technology Classifications, Technology Classifications > Healthcare & Life Sciences
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