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Negative Pressure-Assisted DNA Delivery
Fig.1. Dermal suction induces long-lasting antigen expression and T-cell response. (A) Dermal suction via a small hand-held device with a 6-mm orifice against the skin. Inset: immune response is 100 times stronger when compared with injection alone. (B) Post-suction skin demonstrates no damage nor erythema. (C) and (D): Benchmarking of suction against...
Published: 5/15/2026
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Inventor(s): Hao Lin, Jonathan Singer, David Shreiber, Jerry Shan, Jeffrey Zahn, Emran Lallow, Juliet Melnik, Nandita Jhumur
Keywords(s): Drug Delivery
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > COVID-19, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Vaccine
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Delivery of exogenous protein/peptide cargoes to the cell cytosol
Survival curves of weanling mice immunized with LFn-LACV-Gc or LFn-LACV-N compared with LFn-ZIKV-NS3 and subsequently challenged with LACV
Invention Summary:
Novel T cell-based vaccine was developed by utilizing a fusion protein by binding a target protein or peptide molecule with transport factor derived from Bacteria. The target protein...
Published: 5/12/2026
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Inventor(s): Bobby Brooke Herrera
Keywords(s):
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Infectious Disease, Technology Classifications > Vaccine
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T cell-based vaccines
Survival curves of weanling mice immunized with LFn-LACV-Gc or LFn-LACV-N compared with LFn-ZIKV-NS3 and subsequently challenged with LACV
Invention Summary:
Novel T cell-based vaccine was developed by utilizing a fusion protein by binding a target protein or peptide molecule with transport factor derived from Bacteria. The target protein...
Published: 5/12/2026
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Inventor(s): Bobby Brooke Herrera
Keywords(s):
Category(s): Technology Classifications, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Vaccine
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AmpliFAST - PCR in the Palm of Your Hand
AmpliFast technology for in home diagnostics. Cassette driven diagnostic kit for fast and early detection of infectious diseases.
Invention Summary:
There is a need to develop easy-to-use diagnostic kits based on newly discovered enzymes that enable nucleic acid amplification.
Rutgers researchers have developed a new technology that...
Published: 5/12/2026
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Inventor(s): Bobby Brooke Herrera
Keywords(s):
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > COVID-19, Technology Classifications > Research Tools
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Programmable intracellular RNA scaffolds for integrating sensing and regulation
Co-transactionally folded RNA nanostructures in living cells.
Invention Summary:
Biomarker validation and intracellular RNA detection require tools that are precise, scalable, and capable of capturing complex gene expression patterns. Current approaches, including CRISPR-based systems, RNA interference, and RNA sponge technologies, are often...
Published: 5/15/2026
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Inventor(s): Fei Zhang, Xu (leo) Chang, Jean-Pierre Etchegaray, Maciej Jeziorek
Keywords(s):
Category(s): Technology Classifications > Healthcare & Life Sciences
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Monoclonal, Inducible, and Traceable Mesenchymal Stem Cell Platform for Cell Therapy
This figure illustrates the engineered Mesenchymal Stem Cells are monoclonal, conditionally immortalized (inducible), non-tumorigenic, and traceable in vitro and in vivo (bioluminescent imaging). The engineered MSCs have maintained their multipotency and chemotaxis capability (tumor targeting). The developed MSC platform is capable of delivering...
Published: 5/15/2026
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Inventor(s): Arash Hatefi, Mohammad Massumi
Keywords(s):
Category(s): Technology Classifications > Healthcare & Life Sciences
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Antiviral Compositions for Enterovirus D68 and an FP-Based Method for Validating Candidate Compounds
Invention Portfolio Summary:
Enterovirus D68 (EV-D68) is an RNA virus in the Picornaviridae family, is a re-emerging pediatric pathogen associated with recurrent outbreaks, can cause severe respiratory disease, and has also been linked to acute flaccid myelitis (AFM), whose incidence has risen steadily over the past decade. There are no approved...
Published: 3/27/2026
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Inventor(s):
Keywords(s):
Category(s): Technology Classifications > Healthcare & Life Sciences
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Non-Invasive Closed-Loop Diaphragmatic Pacer for SUDEP Prevention
Invention Summary:
Epileptic seizures can cause central respiratory arrest, a phenomenon called Sudden Unexpected Death in Epilepsy (SUDEP) which needs immediate respiratory support within 3 minutes to avoid death. The absence of reliable biomarkers further limits preventive measures to avoid SUDEP. Here, a wearable diaphragmatic pacer that...
Published: 3/27/2026
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Inventor(s): Benton Purnell, Detlev Boison, Simiao Niu
Keywords(s):
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Medical Devices
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AN INTRA-OCULAR METHOD TO TREAT NEUROPSYCHIATRIC DISORDERS
Figure A indicates in rats the latency as a measure of time to escape from a maze. Figure B indicates AD rats with PRAM therapeutic showed less time to escape the maze, demonstrating improved memory and spatial recall
Invention Summary:
Alzheimer’s disease (AD) affects over 55 million people worldwide and is projected to triple by 2050....
Published: 3/4/2026
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Inventor(s):
Keywords(s):
Category(s): Technology Classifications > Healthcare & Life Sciences
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Enhancers for gene delivery to specific motor neuron subtypes
Enhancers demonstrating motor neuron subtype specificity
Invention Summary:
Specific types of motor neurons become dysfunctional and degenerate in motor neurons diseases like amyotrophic lateral sclerosis and Charcot Marie tooth syndrome. To reduce the risk of toxicity from ubiquitous or non-specific expression of gene therapies, there is...
Published: 2/20/2026
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Inventor(s): Tulsi Patel, Yijia Chen
Keywords(s):
Category(s): Technology Classifications > Healthcare & Life Sciences
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