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Enhancers for gene delivery to specific motor neuron subtypes
Enhancers demonstrating motor neuron subtype specificity
Invention Summary:
Specific types of motor neurons become dysfunctional and degenerate in motor neurons diseases like amyotrophic lateral sclerosis and Charcot Marie tooth syndrome. To reduce the risk of toxicity from ubiquitous or non-specific expression of gene therapies, there is...
Published: 2/20/2026
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Inventor(s): Tulsi Patel, Yijia Chen
Keywords(s):
Category(s): Technology Classifications > Healthcare & Life Sciences
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Electrotherapy for dental implants
In Situ electrochemical repassivation therapy of titanium dental implants can restore corrosion resistance and enhance cellular biocompatibility.
Invention Summary:
Commercially available titanium dental implants have a naturally formed protective titanium oxide (TiO2) passivation layer on their surfaces, which endows the implants with corrosion...
Published: 2/23/2026
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Inventor(s): Georgios Kotsakis, Li Xie
Keywords(s):
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Dental
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Method for Enhancing Immunoregulatory Effect of Stem Cells
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IL-17A promotes MSC-Mediated immunosupressive effect. Changes in cell proliferation as shown in microscopy
Invention Summary:
Autoimmune diseases occur when the immune system attacks the body’s tissue components. Mesenchymal stem/stromal cells (MSCs) have been used as treatment to many autoimmune disorders such as type 1 diabetes,...
Published: 2/24/2026
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Inventor(s): Yufang Shi, Guangwen Ren, Liying Zhang
Keywords(s):
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics, Technology Classifications > Cell Therapy
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Diagnostic Assays and Methods for Detecting Pathogens
A novel sample processing method for the co-extraction of DNA/RNA from Mycobacterium tuberculosis (TB) and SARS-COV-2, complementing a novel near-patient CRISPR test for tuberculosis detection (CRISPR SHINE TB).
Invention Summary:
Tuberculosis and COVID-19 are infectious diseases with high mortality rates caused by Mycobacterium tuberculosis...
Published: 2/20/2026
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Inventor(s): Padmapriya Banada, Nisha Modi, Alexandra Bell, Owen Dunkley, Yingda Xie, Cameron Myhrvold
Keywords(s):
Category(s): Technology Classifications > Diagnostics, Technology Classifications > COVID-19, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Infectious Disease
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Novel diagnostics measures clock gene expression for early detection of fetal alcohol spectrum disorder
Novel salivary diagnostic test to measure circadian clock gene expression in FASD children using saliva samples.
Invention Summary:
Alcohol drinking during pregnancy leads to fetal alcohol spectrum disorder (FASD) accounting for about 2-5% of children in North America. Early diagnosis of FASD is imperative to prevent brain...
Published: 2/20/2026
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Inventor(s): Dipak Sarkar
Keywords(s):
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics
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Prolonged Persistance of Lacticaseibacillus rhamnosus in the Digestive Tract
Recovered CFUs from daily fecal matter after repetitive autologous murine gastrointestinal track gavages. (A) Log10 of the CFU counts from fecal matter obtained after gavage of wild type L. rhamnosus (n=2). (B) Log10 of the CFU counts from fecal matter obtained after gavage of Evolution 1, which used colonies selected from gavage 1 (n=2). (C) Log10...
Published: 2/20/2026
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Inventor(s): Biju Parekkadan, Lorenzo Tosi
Keywords(s):
Category(s): Technology Classifications > Food, Nutrition and Nutraceuticals, Technology Classifications > Healthcare & Life Sciences
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The MaxVac powered toothbrush: Suction Toothbrush and Related Methods
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Vacuum-Tooth Brush Attributes: On-off switch, Vaccum power (hi-low), Easy-Empty (or disposable) fluid & debris collector cup, Ergonomic design, Battery-operated and Affordable.
Invention Summary:
There is a need for a powered toothbrush that has a built-in...
Published: 2/20/2026
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Inventor(s): Maxine Strickland, Glennon Simmons, Dominic Peralta
Keywords(s): Personal Care, Cosmeceuticals
Category(s): Technology Classifications > Dental, Technology Classifications, Technology Classifications > Healthcare & Life Sciences
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MaxVac- Powered Toothbrush with Evacuation Technology
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Vacuum-Tooth Brush Attributes:
On-off switch, Easy-Empty (or disposable) fluid & debris collector cup, Ergonomic design, Battery-operated and Affordable.
Invention Summary:
A novel powered toothbrush that couples a vacuum suction and waste container to an existing toothbrush that automatically removes...
Published: 2/20/2026
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Inventor(s): Maxine Strickland, Vivek Kumar
Keywords(s): Cleaning/Disinfecting Products, Personal Care, Cosmeceuticals
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics, Technology Classifications > Dental, Technology Classifications > Consumer & Household Goods
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Extracellular Vesicles (EVs) from Placenta and Umbilical Cord (UC) Normalize Preeclampsia (PE) Stem Cells
Z. Wang, R. Yang, J. Zhang, et al., “Role of Extracellular Vesicles in Placental Inflammation and Local Immune Balance,” Mediators of Inflammation 2021 (2021): 5558048
Invention Summary:
PE is a serious pregnancy complication affecting 5–8% of pregnancies worldwide and is a leading cause of maternal and fetal morbidity and...
Published: 2/20/2026
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Inventor(s): Lauren Sherman, Jessica Greenberg, Pranela Rameshwar, Shauna Williams
Keywords(s):
Category(s): Technology Classifications > Healthcare & Life Sciences
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Restoration of circadian rhythms impairs formation of cancer stem cells and the growth of tumorspheres
Circadian restoration prevents tumor growth and poor prognosis
Invention Summary:
Triple negative breast cancer (TNBC) is the most aggressive breast cancer subtype, worsened by the presence of cancer stem cells (CSCs). These CSCs increase tumor recurrence and are responsible for tumor initiation and propagation. While conventional chemotherapy...
Published: 2/20/2026
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Inventor(s): Jean-Pierre Etchegaray, Edward Gonzalez, Dahui Wang, Maciej Jeziorek
Keywords(s):
Category(s): Technology Classifications > Cancer, Technology Classifications > Healthcare & Life Sciences
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